Evidence map›Paper›PMID 29520049›Full record

ReviewEye (London, England)2018

Prophylactic laser in age-related macular degeneration: the past, the present and the future.

Quan Findlay, Andrew I Jobling, Kirstan A Vessey, Ursula Greferath, Joanna A Phipps, Robyn H Guymer, Erica L Fletcher

Open access · bronzeAbstract readReview
In one paragraph

Review in Eye (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Medication Trends for Age-Related Macular Degeneration.International journal of molecular sciences · 2021
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Quan FindlayDepartment of Anatomy and Neuroscience, The University of Melbourne, Parkville, 3010, VIC, Australia.
Andrew I JoblingDepartment of Anatomy and Neuroscience, The University of Melbourne, Parkville, 3010, VIC, Australia.
Kirstan A VesseyDepartment of Anatomy and Neuroscience, The University of Melbourne, Parkville, 3010, VIC, Australia.
Ursula GreferathDepartment of Anatomy and Neuroscience, The University of Melbourne, Parkville, 3010, VIC, Australia.
Joanna A PhippsDepartment of Anatomy and Neuroscience, The University of Melbourne, Parkville, 3010, VIC, Australia.
Robyn H GuymerCentre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Parkville, VIC, Australia. rh.guymer@unimelb.edu.au.
Erica L FletcherDepartment of Anatomy and Neuroscience, The University of Melbourne, Parkville, 3010, VIC, Australia.
University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of drusen in the posterior eye is a hallmark feature of the early stages of age-related macular degeneration and their size is an indicator of risk of progression to vision-threatening forms of the disease. Since the initial observations that laser treatment can resolve drusen, there has been great interest in whether laser treatment can be used to reduce the progression of age-related macular degeneration. In this article, we review the development of lasers for the treatment of those with age-related macular degeneration. We provide an overview of the clinical trial results that demonstrated drusen resolution but that had mixed effects on progression of disease. In addition, we provide a summary of the recent developments in pulsed lasers that are designed to reduce the energy applied to the posterior eye to provide the therapeutic effects of conventional continuous wave lasers while reducing the secondary tissue effects.

Indexed as

Laser CoagulationClinical Trials as TopicHumansLasers, SemiconductorMacular DegenerationRetinal Drusen

Identifiers

PMID29520049
PMCPMC5944648
OpenAlexW2790700752

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.