ArticleTranslational psychiatry2018
Lower cognitive control network connectivity in stroke participants with depressive features.
Article in Translational psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Effect of nonpharmacological interventions on poststroke depression: a network meta-analysis.Frontiers in neurology · 2024Pooled it
- Effects of noninvasive brain stimulation in the treatment of poststroke depression: an overview of systematic reviews.Frontiers in neurologyPooled it
- The effect of transcranial direct current stimulation and inhibitory control training on depression and anxiety among post-stroke individuals.BMC neurology · 2025Trial
- Diagnosis and etiology of poststroke depression: A review.World journal of psychiatry · 2025Review
- Study on the Changes of Brain Function in Adolescents With Pain-Depression Comorbidity Based on rs-FMRI.Depression and anxiety · 2025Article
- Acupuncture for arousal combined with repetitive transcranial magnetic stimulation promotes functional reorganization of brain regions in patients with a minimally conscious state: study protocol for a randomized controlled trial.Frontiers in neurology · 2025Article
- The Impact of Post-Stroke Depressive Symptoms on Cognitive Performance in Women and in Men: A 4 Month Prospective Study.Life (Basel, Switzerland) · 2023Article
- The characteristics of brain network in patient with post-stroke depression under cognitive task condition.Frontiers in neuroscience · 2023Article
- No add-on effect of tDCS on fatigue and depression in chronic stroke patients: A randomized sham-controlled trial combining tDCS with computerized cognitive training.Brain and behavior · 2022Review
- Artificially-reconstructed brain images with stroke lesions from non-imaging data: modeling in categorized patients based on lesion occurrence and sparsity.Scientific reports · 2022Article
- Altered functional connectivity in first-episode and recurrent depression: A resting-state functional magnetic resonance imaging study.Frontiers in neurology · 2022Article
- Hyperconnectivity and altered interactions of a nucleus accumbens network in post-stroke depression.Brain communications · 2022Article
- Emotional and qualitative outcomes among patients with left and right hemisphere stroke.Frontiers in neurology · 2022Article
- A comparative study of amplitude of low-frequence fluctuation of resting-state fMRI between the younger and older treatment-resistant depression in adults.Frontiers in neuroscience · 2022Article
- Effects of Optimized Acupuncture and Moxibustion Treatment on Depressive Symptoms and Executive Functions in Patients With Post-Stroke Depression: Study Protocol for a Randomized Controlled Trial.Frontiers in neurology · 2022Article
- Neural Substrates of Poststroke Depression: Current Opinions and Methodology Trends.Frontiers in neuroscience · 2022Review
- Improving Depressive Symptoms of Post-stroke Depression Using the Shugan Jieyu Capsule: A Resting-State Functional Magnetic Resonance Imaging Study.Frontiers in neurology · 2022Article
- Altered functional connectivity within default mode network after rupture of anterior communicating artery aneurysm.Frontiers in aging neuroscience · 2022Article
- Electroacupuncture Ameliorates Depressive-Like Behaviors in Poststroke Rats via Activating the tPA/BDNF/TrkB Pathway.Neuropsychiatric disease and treatment · 2021Article
- Lesions in the right Rolandic operculum are associated with self-rating affective and apathetic depressive symptoms for post-stroke patients.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Around one-third of people develop depression following ischaemic stroke, yet the underlying mechanisms are poorly understood. Post-stroke depression has been linked to frontal infarcts, mainly lesions in the left dorsolateral prefrontal cortex (DLPFC). But depression is a network disorder that cannot be fully characterised through lesion-symptom mapping. Researchers of depression in non-stroke populations have successfully tapped into the cognitive control network (CCN) using the bilateral DLPFC as a seed, and found that CCN resting-state connectivity is reduced in even mildly depressed subjects, compared to healthy controls. Hence, we aimed to investigate the association between post-stroke depressive features and the CCN resting-state connectivity in a stroke population. We analysed DLPFC resting-state connectivity in 64 stroke participants, 20 of whom showed depressive features assessed with the Patient Health Questionnaire (PHQ-9) at 3 months after stroke. We directly compared groups showing symptoms of depression with those who did not, and performed a regression with PHQ-9 scores in all participants, controlling for age, gender, lesion volume and stroke severity. Post-stroke depression was associated with lower connectivity between the left DLPFC and the right supramarginal gyrus (SMG) in both group and regression analyses. Neither the seed nor the results overlapped with stroke lesions. These findings confirm an important role of the left DLPFC in post-stroke depression, but now show that large-scale network disruptions following stroke associated with depressive features occur without lesions in the DLPFC.
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