ArticleG3 (Bethesda, Md.)2018
Functional Validation of Candidate Genes Detected by Genomic Feature Models.
Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
16 citing papers in PubMed.
- Female genetic variation controlling timing of mating plug ejection inbioRxiv : the preprint server for biology · 2026Article
- Glucocorticoid Receptor Gene Polymorphisms and Femoral Head Osteonecrosis.Medicina (Kaunas, Lithuania) · 2026Article
- Association Between Catenin Beta-1 (CTNNB1) Gene Polymorphisms and Non-Traumatic Osteonecrosis of the Femoral Head (ONFH).Current issues in molecular biology · 2026Article
- The role of genetic variation in shaping phenotypic responses to diet in aging Drosophila melanogaster.Heredity · 2025Article
- Wings of Discovery: UsingCells · 2025Review
- Highly Efficient Generation of Germline Mutations Using CRISPR/Cas9 in the Speckled Wood ButterflyEcology and evolution · 2025Article
- Review
- Experimental Evolution in a Warming World: The Omics Era.Molecular biology and evolution · 2024Review
- Focus on your locus with a massively parallel reporter assay.Journal of neurodevelopmental disorders · 2022Review
- Accounting for genetic architecture for body weight improves accuracy of predicting breeding values in a commercial line of broilers.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2021Article
- Article
- In vivo identification and validation of novel potential predictors for human cardiovascular diseases.PloS one · 2021Article
- Leveraging Multiple Layers of Data To PredictG3 (Bethesda, Md.) · 2020Article
- Genomic Prediction Informed by Biological Processes Expands Our Understanding of the Genetic Architecture Underlying Free Amino Acid Traits in DryG3 (Bethesda, Md.) · 2020Article
- Genetic Networks Underlying Natural Variation in Basal and Induced Activity Levels inG3 (Bethesda, Md.) · 2020Article
- Genetic Signatures of Drug Response Variability inGenetics · 2019Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Understanding the genetic underpinnings of complex traits requires knowledge of the genetic variants that contribute to phenotypic variability. Reliable statistical approaches are needed to obtain such knowledge. In genome-wide association studies, variants are tested for association with trait variability to pinpoint loci that contribute to the quantitative trait. Because stringent genome-wide significance thresholds are applied to control the false positive rate, many true causal variants can remain undetected. To ameliorate this problem, many alternative approaches have been developed, such as genomic feature models (GFM). The GFM approach tests for association of set of genomic markers, and predicts genomic values from genomic data utilizing prior biological knowledge. We investigated to what degree the findings from GFM have biological relevance. We used the
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.