Trial reportJournal of medical Internet research2018
Internet-Based Cognitive Behavioral Therapy for Symptoms of Depression and Anxiety Among Patients With a Recent Myocardial Infarction: The U-CARE Heart Randomized Controlled Trial.
Trial report in Journal of medical Internet research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01504191 (A Randomized Controlled Study of the Effects of Internet-based Cognitive Behavior Therapy on Depression and Anxiety in Patients With a Previous Myocardial Infarction), which is not on this map. Cited by 55 papers, 6 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Controlled Study of the Effects of Internet-based Cognitive Behavior Therapy on Depression and Anxiety in Patients With a Previous Myocardial Infarction
Who cites it
55 citing papers in PubMed, 6 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- Effects of cognitive behavioral therapy on anxiety and depression in patients with myocardial infarction: a systematic review and meta-analysis.Frontiers in psychology · 2026Pooled it
- The Influence of eHealth Stress Management Interventions on Psychological Health Parameters in Patients With Cardiovascular Disease: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Psychological eHealth Interventions for Patients With Cardiovascular Diseases: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Psychological and pharmacological interventions for depression in patients with coronary artery disease.The Cochrane database of systematic reviews · 2021Pooled it
- Effect of Engagement With Digital Interventions on Mental Health Outcomes: A Systematic Review and Meta-Analysis.Frontiers in digital health · 2021Pooled it
- Modes of e-Health delivery in secondary prevention programmes for patients with coronary artery disease: a systematic review.BMC health services research · 2019Pooled it
- The effect of listening to the voice recording of relatives on chest pain, anxiety and depression in patients hospitalized in the coronary intensive care unit: A randomized controlled trial.Nursing in critical care · 2025Trial
- Metacognitive therapy home-based self-help for anxiety and depression in cardiovascular disease patients in the UK: A single-blind randomised controlled trial.PLoS medicine · 2023Trial
- The experience of participating in an internet-based cognitive behavioral therapy program among patients with cardiovascular disease and depression: a qualitative interview study.BMC psychiatry · 2022Trial
- Internet-Based Cognitive Behavioral Therapy for Patients Reporting Symptoms of Anxiety and Depression After Myocardial Infarction: U-CARE Heart Randomized Controlled Trial Twelve-Month Follow-up.Journal of medical Internet research · 2021Trial
- Predicting Adherence to Internet-Delivered Psychotherapy for Symptoms of Depression and Anxiety After Myocardial Infarction: Machine Learning Insights From the U-CARE Heart Randomized Controlled Trial.Journal of medical Internet research · 2018Trial
- Effect of 5E rehabilitation management model on physical and psychological health of elderly patients with cerebral infarction: a randomized controlled trial.BMC nursing · 2026Article
- Development of a guided internet-based psychological intervention for patients with ischemic heart disease and comorbid anxiety and/or depression: A patient and public involvement study.Internet interventions · 2025Article
- E-Mental Health Interventions in Inpatient Care: Scoping Review.Journal of medical Internet research · 2025Article
- Harnessing an Artificial Intelligence-Based Large Language Model With Personal Health Record Capability for Personalized Information Support in Postsurgery Myocardial Infarction: Descriptive Qualitative Study.Journal of medical Internet research · 2025Article
- Cognitive behavioural therapy targeting cardiac anxiety post-myocardial infarction: results from two sequential pilot studies.European heart journal open · 2025Article
- Development of an online psychological intervention to prevent depression in patients with atrial fibrillation: lessons learned in a user-centered design study.Pilot and feasibility studies · 2025Article
- A systematic review and meta analysis on digital mental health interventions in inpatient settings.NPJ digital medicine · 2024Article
- Article
- Mapping interventional components and behavior change techniques used to promote self-management in people with multimorbidity: a scoping review.Health psychology review · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSymptoms of depression and anxiety are common after a myocardial infarction (MI). Internet-based cognitive behavioral therapy (iCBT) has shown good results in other patient groups.
objectiveThe aim of this study was to evaluate the effectiveness of an iCBT treatment to reduce self-reported symptoms of depression and anxiety among patients with a recent MI.
methodsIn total, 3928 patients were screened for eligibility in 25 Swedish hospitals. Of these, 239 patients (33.5%, 80/239 women, mean age 60 years) with a recent MI and symptoms of depression or anxiety were randomly allocated to a therapist-guided, 14-week iCBT treatment (n=117), or treatment as usual (TAU; n=122). The iCBT treatment was designed for post-MI patients. The primary outcome was the total score of the Hospital Anxiety and Depression Scale (HADS) 14 weeks post baseline, assessed over the internet. Treatment effect was evaluated according to the intention-to-treat principle, with multiple imputations. For the main analysis, a pooled treatment effect was estimated, controlling for age, sex, and baseline HADS.
resultsThere was a reduction in HADS scores over time in the total study sample (mean delta=-5.1, P<.001) but no difference between the study groups at follow-up (beta=-0.47, 95% CI -1.95 to 1.00, P=.53). Treatment adherence was low. A total of 46.2% (54/117) of the iCBT group did not complete the introductory module.
conclusionsiCBT treatment for an MI population did not result in lower levels of symptoms of depression or anxiety compared with TAU. Low treatment adherence might have influenced the result.
trial registrationClinicalTrials.gov NCT01504191; https://clinicaltrials.gov/ct2/show/NCT01504191 (Archived at Webcite at http://www.webcitation.org/6xWWSEQ22).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.