Evidence map›Paper›PMID 29519244›Full record

ReviewJournal of medical case reports2018

Acute liver failure complication of brucellosis infection: a case report and review of the literature.

Julio César García Casallas, Walter Villalobos Monsalve, Sara Consuelo Arias Villate, Ingrid Marisol Fino Solano

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Journal of medical case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 25 citations in OpenAlex.

  1. FulminantCase reports in infectious diseases · 2026
    Article
  2. [Research progress on brucellosis combined with liver injury].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Prevalence ofHealth science reports · 2023
    Article
  8. SAGE open medical case reports · 2023
    Article
  9. Article
  10. Article
  11. Proceedings (Baylor University. Medical Center) · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Julio César García CasallasInternal Medicine and Clinical Pharmacology, Department of Clinical Pharmacology and Therapeutics, Clínica Universidad de La Sabana, Chía, Colombia. julio.garcia@unisabana.edu.co.
Walter Villalobos MonsalveInternal Medicine, Clínica Universidad de La Sabana, Chía, Colombia.
Sara Consuelo Arias VillateClinical Pharmacology Service, University of La Sabana, Chía, Colombia.
Ingrid Marisol Fino SolanoClinical Pharmacology Resident, Clinical Pharmacology Department, University of La Sabana, Chía, Colombia.
Universidad de La Sabana · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBrucellosis is one of the most widespread zoonoses worldwide. It can affect any organ system, particularly the gastrointestinal system, but there is no report of acute liver failure as a brucellosis complication. CASE PRESENTATION: We present a case of acute liver failure secondary to brucellosis infection. A 75-year-old Hispanic man presented to a University Hospital in Chía, Colombia, with a complaint of 15 days of fatigue, weakness, decreased appetite, epigastric abdominal pain, jaundice, and 10 kg weight loss. On examination in an emergency room, abdomen palpation was normal with hepatosplenomegaly and the results of a liver function test were elevated. The diagnosis of brucellosis was confirmed by epidemiological contact and positive Rose Bengal agglutination with negative enzyme-linked immunosorbent assay immunoglobulin M for Brucella. He was then treated with doxycycline plus trimethoprim/sulfamethoxazole, with a favorable clinical outcome.

conclusionsThe clinical presentation of brucellosis can be very imprecise because it can affect any organ system; however, there is no report of acute liver failure as a brucellosis complication. This is the first reported case in the Colombian literature of acute liver failure due to brucellosis. We found this case to be of interest because it could be taken into account for diagnosis in future appearances and we described adequate treatment and actions to be taken at presentation.

Indexed as

Liver Function TestsAgedAnimal HusbandryAnti-Bacterial AgentsBrucella melitensisBrucellosisColombiaDoxycyclineEnzyme-Linked Immunosorbent AssayHumansLiver Failure, AcuteMaleOccupational DiseasesRose BengalTreatment OutcomeTrimethoprim, Sulfamethoxazole Drug CombinationAnti-Bacterial AgentsDoxycyclineRose BengalRose Bengal BTrimethoprim, Sulfamethoxazole Drug CombinationAcute liver failureBrucellosisParasitic infectionsZoonosis

Identifiers

PMID29519244
PMCPMC5844122
OpenAlexW2792073702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.