Evidence map›Paper›PMID 29518972›Full record

ArticleInternational journal of molecular sciences2018

The ADAMTS5 Metzincin Regulates Zebrafish Somite Differentiation.

Carolyn M Dancevic, Yann Gibert, Joachim Berger, Adam D Smith, Clifford Liongue, Nicole Stupka, Alister C Ward, Daniel R McCulloch

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Treatment of DystrophicBiomolecules · 2020
    Article
  2. Extracellular Matrix in Development and Disease.International journal of molecular sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Carolyn M DancevicSchool of Medicine, Deakin University, Waurn Ponds, Victoria 3216, Australia. carolyn.dancevic@deakin.edu.au.
Yann GibertSchool of Medicine, Deakin University, Waurn Ponds, Victoria 3216, Australia. y.gibert@deakin.edu.au.
Joachim BergerAustralian Regenerative Medicine Institute, Monash University, Clayton, Victoria 3800, Australia. joachim.berger@monash.edu.ORCID 0000-0002-7859-545X
Adam D SmithSchool of Medicine, Deakin University, Waurn Ponds, Victoria 3216, Australia. adam.smith@bio-strategy.com.
Clifford LiongueSchool of Medicine, Deakin University, Waurn Ponds, Victoria 3216, Australia. c.liongue@deakin.edu.au.ORCID 0000-0002-1646-4905
Nicole StupkaSchool of Medicine, Deakin University, Waurn Ponds, Victoria 3216, Australia. nicole.stupka@deakin.edu.au.ORCID 0000-0002-1000-1707
Alister C WardSchool of Medicine, Deakin University, Waurn Ponds, Victoria 3216, Australia. award@deakin.edu.au.
Daniel R McCullochSchool of Medicine, Deakin University, Waurn Ponds, Victoria 3216, Australia. daniel.mcculloch@uq.net.au.
Deakin University · AUAustralian Regenerative Medicine Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ADAMTS5 metzincin, a secreted zinc-dependent metalloproteinase, modulates the extracellular matrix (ECM) during limb morphogenesis and other developmental processes. Here, the role of ADAMTS5 was investigated by knockdown of zebrafish

Indexed as

Cell DifferentiationADAMTS5 ProteinAnimalsEmbryo, NonmammalianExtracellular SpaceGene Expression Regulation, DevelopmentalGene SilencingHedgehog ProteinsMorphogenesisMuscle DevelopmentSignal TransductionSomitesZebrafishADAMTS5 ProteinHedgehog ProteinsADAMTSextracellular matrixmetalloproteinasemusclesomitezebrafish

Identifiers

PMID29518972
PMCPMC5877627
OpenAlexW2793738750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.