SynthesisEuropean journal of obstetrics, gynecology, and reproductive biology2018
Duration of spontaneous labour in 'low-risk' women with 'normal' perinatal outcomes: A systematic review.
Synthesis in European journal of obstetrics, gynecology, and reproductive biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Routine vaginal examinations compared to other methods for assessing progress of labour to improve outcomes for women and babies at term.The Cochrane database of systematic reviews · 2022Pooled it
- Duration of the second and third stages of labor and risk of postpartum hemorrhage: a cohort study stratified by parity.BMC pregnancy and childbirth · 2025Trial
- Balancing safety and comfort in childbirth: a grounded theory of labor progress assessment among frontline obstetric healthcare providers.BMC nursing · 2026Article
- A Comparative Observational Study on the WHO Labour Care Guide Versus the WHO Modified Partograph on Labour Outcome.Cureus · 2026Article
- Article
- Factors associated with women's childbirth experience in Slovakia: A cross-sectional analysis of overall childbirth experience and individual domains of the Childbirth Experience Questionnaire 2 (CEQ2).European journal of midwifery · 2026Article
- Article
- Article
- Association between labor duration in transvaginal deliveries and the risk of neonatal intensive care unit admission for newborns.Frontiers in pediatrics · 2025Article
- Article
- Duration of labor in consecutive deliveries: a retrospective data analysis.Archives of gynecology and obstetrics · 2024Article
- Incidence of histologic chorioamnionitis in a rural community hospital.Irish journal of medical science · 2024Article
- The Potential Role of Wearable Inertial Sensors in Laboring Women with Walking Epidural Analgesia.Sensors (Basel, Switzerland) · 2024Article
- Maternal periodontitis may cause lower birth weight in children: genetic evidence from a comprehensive Mendelian randomization study on periodontitis and pregnancy.Clinical oral investigations · 2024Article
- Circadian characteristics of term and preterm labors.Scientific reports · 2024Article
- Postpartum hemorrhage in electronic health records: risk factors at admission and in-hospital occurrence.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2024Article
- Changes of serum cortisol during pregnancy and labor initiation: an onsite cross-sectional study.Frontiers in endocrinology · 2024Article
- Labor patterns of spontaneous first-stage labor in Chinese women with normal neonatal outcomes.PloS one · 2024Observational
- Customization and acceptability of the WHO labor care guide to improve labor monitoring among health workers in Uganda. An iterative development, mixed method study.PLOS global public health · 2024Article
- First stage of labour duration and associated risk of adverse neonatal outcomes.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundDespite decades of research, the concept of normality in labour in terms of its progression and duration is not universal or standardized. However, in clinical practice, it is important to define the boundaries that distinguish what is normal from what is abnormal to enable women and care providers have a shared understanding of what to expect and when labour interventions are justified.
objectivesTo synthesise available evidence on the duration of latent and active first stage and the second stage of spontaneous labour in women at low risk of complications with 'normal' perinatal outcomes. SEARCH STRATEGY: PubMed, EMBASE, CINAHL, POPLINE, Global Health Library, and reference lists of eligible studies. SELECTION CRITERIA: Observational studies and other study designs. DATA COLLECTION AND ANALYSIS: Four authors extracted data on: maternal characteristics; labour interventions; duration of latent first stage, active first stage, and second stage of labour; and the definitions of onset of latent and active first stage, and second stage where reported. Heterogeneity in the included studies precluded meta-analysis and data were presented descriptively. MAIN
resultsThirty-seven studies reporting the duration of first and/or second stages of labour for 208,000 women met our inclusion criteria. Among nulliparous women, the median duration of active first stage (when the starting reference point was 4 cm) ranged from 3.7-5.9 h (95th percentiles: 14.5-16.7 h). With active phase starting from 5 cm, the median duration was from 3.8-4.3 h (95th percentiles: 11.3-12.7 h). The median duration of second stage ranged from 14 to 66 min (95th percentiles: 65-138 min) and from 6 to 12 min (95th percentiles: 58-76 min) in nulliparous and parous women, respectively. Sensitivity analyses excluding first and second stage interventions did not significantly impact on these findings
conclusionsThe duration of spontaneous labour in women with good perinatal outcomes varies from one woman to another. Some women may experience labour for longer than previously thought, and still achieve a vaginal birth without adverse perinatal outcomes. Our findings question the rigid limits currently applied in clinical practice for the assessment of prolonged first or second stage that warrant obstetric intervention.
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