Evidence map›Paper›PMID 29518434›Full record

ArticleFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association2018

Pharmacokinetics of [

Jessica M Hummel, Erin P Madeen, Lisbeth K Siddens, Sandra L Uesugi, Tammie McQuistan, Kim A Anderson, Kenneth W Turteltaub, Ted J Ognibene, Graham Bench, Sharon K Krueger and 5 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Multi omics network toxicology andFrontiers in cell and developmental biology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Jessica M HummelDepartment of Nutrition and Dietetics, Oregon State University, Corvallis, OR, USA; Superfund Research Program, Oregon State University, Corvallis, OR, USA.
Erin P MadeenSuperfund Research Program, Oregon State University, Corvallis, OR, USA; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA.
Lisbeth K SiddensSuperfund Research Program, Oregon State University, Corvallis, OR, USA; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA; Linus Pauling Institute, Oregon State University, Corvallis, OR, USA.
Sandra L UesugiLinus Pauling Institute, Oregon State University, Corvallis, OR, USA.
Tammie McQuistanLinus Pauling Institute, Oregon State University, Corvallis, OR, USA.
Kim A AndersonSuperfund Research Program, Oregon State University, Corvallis, OR, USA; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA.
Kenneth W TurteltaubBiosciences and Biotechnology Division, Lawrence Livermore National Laboratory, Livermore, CA, USA.
Ted J OgnibeneCenter for Accelerator Mass Spectrometry, Lawrence Livermore National Laboratory, Livermore, CA, USA.
Graham BenchCenter for Accelerator Mass Spectrometry, Lawrence Livermore National Laboratory, Livermore, CA, USA.
Sharon K KruegerLinus Pauling Institute, Oregon State University, Corvallis, OR, USA.
Stuart HarrisConfederated Tribes of the Umatilla Indian Reservation, Nixyáawii Governance Center, Pendelton, OR, USA.
Jordan SmithSuperfund Research Program, Oregon State University, Corvallis, OR, USA; Chemical Biology and Exposure Science, Pacific Northwest National Laboratory, Richland, WA, USA.
Susan C TiltonSuperfund Research Program, Oregon State University, Corvallis, OR, USA; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA.
William M BairdSuperfund Research Program, Oregon State University, Corvallis, OR, USA; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA.
David E WilliamsSuperfund Research Program, Oregon State University, Corvallis, OR, USA; Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA; Linus Pauling Institute, Oregon State University, Corvallis, OR, USA. Electronic address: david.williams@oregonstate.edu.
Oregon State University · USLawrence Livermore National Laboratory · USConfederated Tribes of Warm Springs · USPacific Northwest National Laboratory · US

Funding

Research Experience and Training Coordination CoreP42ES016465 · NIEHS · OREGON STATE UNIVERSITY · PI Robyn L Tanguay · 2009 to 2026
$52.5M
Resource for the Development of Biomedical Accelerator Mass Spectrometry (AMS)P41GM103483 · NIGMS · UNIVERSITY OF CALIF-LAWRNC LVRMR NAT LAB · PI TURTELTAUB, KENNETH W. · 2012 to 2019
$12.0M
MODE OF ACTION OF ENVIRONMENTAL TOXICANTST32ES007060 · NIEHS · OREGON STATE UNIVERSITY · PI Jamie DeWitt, Siva Kumar Kolluri · 1985 to 2026
$11.6M
Benzo[a]pyrene Micro-dosing of Humans: A New Tool for Exposure, Risk Assessment and PreventionR01ES028600 · NIEHS · OREGON STATE UNIVERSITY · PI WILLIAMS, DAVID E · 2018 to 2022
$2.5M
NIEHS NIH HHS P42 ES016465NIEHS NIH HHS R01 ES028600NIEHS NIH HHS T32 ES007060NIGMS NIH HHS P41 GM103483
6 · The paper itself

Abstract

Benzo[a]pyrene (BaP), a polycyclic aromatic hydrocarbon (PAH), is a known human carcinogen. In non-smoking adults greater than 95% of BaP exposure is through diet. The carcinogenicity of BaP is utilized by the U.S. EPA to assess relative potency of complex PAH mixtures. PAH relative potency factors (RPFs, BaP = 1) are determined from high dose animal data. We employed accelerator mass spectrometry (AMS) to determine pharmacokinetics of [

Indexed as

AdultAgedAnimalsBenzo(a)pyreneCarbon RadioisotopesCarcinogensCookingFemaleFish ProductsFood SafetyHumansMaleMiddle AgedPolycyclic Aromatic HydrocarbonsSalmonYoung AdultBenzo(a)pyreneCarbon-14Carbon RadioisotopesCarcinogensPolycyclic Aromatic HydrocarbonsAccelerator mass spectrometryBenzo[a]pyreneDietary polycyclic aromatic hydrocarbonsPharmacokinetics

Identifiers

PMID29518434
PMCPMC5935529
OpenAlexW2792834372

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.