Evidence map›Paper›PMID 29518418›Full record

Trial reportThe Journal of allergy and clinical immunology2018

Glutathione and arginine levels: Predictors for acetaminophen-associated asthma exacerbation?

Claudia R Morris, David T Mauger, Jung H Suh, Wanda Phipatanakul, William J Sheehan, James N Moy, Ian M Paul, Stanley J Szefler, Daniel J Jackson, Anne M Fitzpatrick and 1 more

Open access · greenAbstract readLetterRandomized Controlled Trial
In one paragraph

Trial report in The Journal of allergy and clinical immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Acetaminophen is both bronchodilatory and bronchoprotective in human precision cut lung slice airways.Xenobiotica; the fate of foreign compounds in biological systems · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 1 country.

Claudia R MorrisDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Ga.
David T MaugerDepartment of Public Health Sciences, College of Medicine, Penn State University, Hershey, Pa.
Jung H SuhChildren's Hospital Oakland Research Institute, Oakland, Calif.
Wanda PhipatanakulDivision of Allergy/Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
William J SheehanDivision of Allergy/Immunology, Boston Children's Hospital, Harvard Medical School, Boston, Mass.
James N MoyStroger Hospital of Cook County, Department of Pediatrics, Rush University Medical Center, Chicago, Ill.
Ian M PaulDepartment of Pediatrics, College of Medicine, Penn State University, Hershey, Pa.
Stanley J SzeflerChildren's Hospital Colorado, the Breathing Institute, and the University of Colorado School of Medicine, Aurora, Colo.
Daniel J JacksonPediatrics, Section of Allergy, Immunology and Rheumatology, University of Wisconsin School of Medicine and Public Health, Madison, Wis.
Anne M FitzpatrickDepartment of Pediatrics, Emory University School of Medicine, Atlanta, Ga. Electronic address: anne.fitzpatrick@emory.edu.
National Institutes of Health/National Heart, Lung, and Blood Institute AsthmaNet
Boston Children's Hospital · USEmory University · USChildren's Hospital Colorado · USPenn State Milton S. Hershey Medical Center · USPennsylvania State University · USUniversity of Wisconsin–Madison · USHarvard University · USJohn H. Stroger, Jr. Hospital of Cook County · USRush University Medical Center · US

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Data Coordinating Center for the NHLBI Asthma Network (AsthmaNet)U10HL098115 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MAUGER, DAVID T. · 2009 to 2015
$57.6M
Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
PEDIATRIC ASTHMA NETWORK DATA COORDINATING CENTERU10HL064313 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MAUGER, DAVID T. · 1999 to 2008
$18.3M
AsthmaNet: Brigham and Women's Hospital & Children's Hospital BostonU10HL098102 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ISRAEL, ELLIOT, PHIPATANAKUL, WANDA · 2009 to 2015
$5.5M
Clinical Centers for the NHLBI Asthma Network (AsthmaNet)U10HL098075 · NHLBI · NATIONAL JEWISH HEALTH · PI SZEFLER, STANLEY J., WECHSLER, MICHAEL E · 2009 to 2015
$5.1M
AsthmaNet: UW-Madison Clinical and Translational Research CenterU10HL098090 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI LEMANSKE, ROBERT F, SORKNESS, CHRISTINE ANNE · 2009 to 2015
$4.8M
UCSF AsthmaNet Clinical CenterU10HL098107 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CABANA, MICHAEL D, LAZARUS, STEPHEN C · 2009 to 2015
$4.8M
NCATS NIH HHS UL1 TR000439NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR001082NCATS NIH HHS UL1 TR002345NCATS NIH HHS UL1 TR002378NHLBI NIH HHS U10 HL064313NHLBI NIH HHS U10 HL098075NHLBI NIH HHS U10 HL098090NHLBI NIH HHS U10 HL098096NHLBI NIH HHS U10 HL098098NHLBI NIH HHS U10 HL098102NHLBI NIH HHS U10 HL098103NHLBI NIH HHS U10 HL098107NHLBI NIH HHS U10 HL098112NHLBI NIH HHS U10 HL098115NHLBI NIH HHS U10 HL098177NIAID NIH HHS K23 AI104780NIAID NIH HHS K24 AI106822NIAID NIH HHS L40 AI107923
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AcetaminophenAnalgesics, Non-NarcoticAnti-Asthmatic AgentsArginineAsthmaBiomarkersChild, PreschoolFemaleFluticasoneGlutathioneHumansInfantMaleOrnithineAcetaminophenAnalgesics, Non-NarcoticAnti-Asthmatic AgentsArginineBiomarkersFluticasoneGlutathioneOrnithine

Identifiers

PMID29518418
PMCPMC6035773
OpenAlexW2791675461

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.