Evidence map›Paper›PMID 29518206›Full record

ReviewEndocrine reviews2018

The Science of Obesity Management: An Endocrine Society Scientific Statement.

George A Bray, William E Heisel, Ashkan Afshin, Michael D Jensen, William H Dietz, Michael Long, Robert F Kushner, Stephen R Daniels, Thomas A Wadden, Adam G Tsai and 5 more

Abstract readReview
In one paragraph

Review in Endocrine reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 402 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
402citing papers in PubMed, 3 pooled it
45.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

402 citing papers in PubMed, 3 syntheses or guidelines pooled it, 800 citations in OpenAlex.

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342 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 14 institutions in 1 country.

George A BrayDepartment of Clinical Obesity, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana.
William E HeiselInstitute of Health Metrics and Evaluation University of Washington, Seattle, Washington.
Ashkan AfshinInstitute of Health Metrics and Evaluation University of Washington, Seattle, Washington.
Michael D JensenDepartment of Medicine, Mayo Clinic, Rochester, Minnesota.
William H DietzRedstone Global Center for Prevention and Wellness, Milken Institute School of Public Health, George Washington University, Washington, District of Columbia.
Michael LongRedstone Global Center for Prevention and Wellness, Milken Institute School of Public Health, George Washington University, Washington, District of Columbia.
Robert F KushnerNorthwestern Feinberg School of Medicine, Chicago, Illinois.
Stephen R DanielsDepartment of Pediatrics, University of Colorado Children Hospital, Denver, Colorado.
Thomas A WaddenDepartment of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Adam G TsaiKaiser Permanente Colorado, Denver, Colorado.
Frank B HuDepartment of Nutrition and Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
John M JakicicUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Donna H RyanDepartment of Clinical Obesity, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana.
Bruce M WolfeOregon Health and Science University, Portland, Oregon.
Thomas H IngeDepartment of Surgery, University of Colorado Denver, Aurora, Colorado.
University of Washington · USChildren's Hospital Colorado · USGeorge Washington University · USHarvard University · USKaiser Permanente · USLouisiana State University · USMayo Clinic · USMilken Institute · USNorthwestern University · USOregon Health & Science University · USPennington Biomedical Research Center · USUniversity of Colorado Denver · USUniversity of Pennsylvania · USUniversity of Pittsburgh · US

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
Transgenic CoreP30DK046200 · NIDDK · TUFTS MEDICAL CENTER · PI CORKEY, BARBARA E. · 1992 to 2021
$25.0M
REGIONAL FATTY ACID METABOLISM IN HUMANSR01DK045343 · NIDDK · MAYO CLINIC ROCHESTER · PI MICHAEL D. JENSEN · 1992 to 2026
$12.9M
FFA METABOLISM IN DIFFERENT TYPES OF HUMAN OBESITYR01DK040484 · NIDDK · MAYO CLINIC ROCHESTER · PI MICHAEL D. JENSEN · 1993 to 2026
$8.2M
Free Fatty Acid Metabolism in Different Types of Human ObesityR37DK040484 · NIDDK · MAYO CLINIC ROCHESTER · PI JENSEN, MICHAEL D. · 2003 to 2012
$4.1M
NIDDK NIH HHS P30 DK046200NIDDK NIH HHS R01 DK040484NIDDK NIH HHS R01 DK045343NIDDK NIH HHS R37 DK040484
6 · The paper itself

Abstract

The prevalence of obesity, measured by body mass index, has risen to unacceptable levels in both men and women in the United States and worldwide with resultant hazardous health implications. Genetic, environmental, and behavioral factors influence the development of obesity, and both the general public and health professionals stigmatize those who suffer from the disease. Obesity is associated with and contributes to a shortened life span, type 2 diabetes mellitus, cardiovascular disease, some cancers, kidney disease, obstructive sleep apnea, gout, osteoarthritis, and hepatobiliary disease, among others. Weight loss reduces all of these diseases in a dose-related manner-the more weight lost, the better the outcome. The phenotype of "medically healthy obesity" appears to be a transient state that progresses over time to an unhealthy phenotype, especially in children and adolescents. Weight loss is best achieved by reducing energy intake and increasing energy expenditure. Programs that are effective for weight loss include peer-reviewed and approved lifestyle modification programs, diets, commercial weight-loss programs, exercise programs, medications, and surgery. Over-the-counter herbal preparations that some patients use to treat obesity have limited, if any, data documenting their efficacy or safety, and there are few regulatory requirements. Weight regain is expected in all patients, especially when treatment is discontinued. When making treatment decisions, clinicians should consider body fat distribution and individual health risks in addition to body mass index.

Indexed as

Practice Guidelines as TopicSocieties, MedicalAdultChildHumansObesity

Identifiers

PMID29518206
PMCPMC5888222
OpenAlexW2790337982

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.