ArticleMedical science monitor : international medical journal of experimental and clinical research2018
Risk Factors for Depression in Patients with Chronic Obstructive Pulmonary Disease.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Association between mental health and chronic obstructive pulmonary disease (COPD) outcomes: systematic review and meta-analysis.BMJ open respiratory research · 2026Pooled it
- Exploring Anxiety Triggers in Non-sedated Upper Gastrointestinal Endoscopy: A Prospective Analysis.Digestive diseases and sciences · 2025Observational
- Biological sex and age-associated changes in muscle and brain health in Chronic Obstructive Pulmonary Disease: A large cross-sectional study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2025Article
- Supportive care needs of the family caregivers of urostomy patients: a qualitative study.Scientific reports · 2025Article
- The Impact of Anxiety and Depression in Chronic Obstructive Pulmonary Disease.Advances in respiratory medicine · 2023Review
- Association between depression and lung function in college students.Frontiers in public health · 2023Article
- Metabolomics Based on Peripheral Blood Mononuclear Cells to Dissect the Mechanisms of Chaigui Granules for Treating Depression.ACS omega · 2022Article
- The landscape of cognitive function in recovered COVID-19 patients.Journal of psychiatric research · 2020Article
- Fractional Exhaled Nitric Oxide (FeNO) Combined with Pulmonary Function Parameters Shows Increased Sensitivity and Specificity for the Diagnosis of Cough Variant Asthma in Children.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND Depression is a major comorbidity in Chronic Obstructive Pulmonary Disease (COPD). The aim of this study was to explore cytokine levels, and socio-demographic and clinical factors that may affect COPD-related depression. MATERIAL AND METHODS This prospective study enrolled 53 consecutive COPD patients, without any other lower respiratory tract diseases, psychiatric disorders, family history or cognitive disorders, who were hospitalized in the Department of Respiratory Medicine of Hefei First People's Hospital, China between October 2015 and October 2016. All patients were investigated for depression, and the serum levels of C-reactive protein (CRP), interleukin-6 (IL-6), interleukin-8 (IL-8) and Tumor Necrosis Factor-α (TNF-α) were measured. The factors that may affect COPD-related depression were analyzed. RESULTS There were 40 (75.47%) patients with depression. There were differences in gender, smoking, time of cough, education, forced expiratory volume in the first second (FEV1) and serum CRP levels between COPD patients with or without depression. In a univariate analysis, gender, smoking, education, FEV1, time of cough and serum CRP level were associated with depression. In a multivariate logistic regression model, serum CRP level and FEV1 were risk factors for depression. CONCLUSIONS Male patients, heavy smoking, higher academic qualifications, cough, and high serum CRP level were linked to higher incidence rate of depression. High serum CRP level and low FEV1 were the risk factors for COPD-related depression.
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