Observational studyBlood transfusion = Trasfusione del sangue2018
Intravenous iron administration for post-operative anaemia management after colorectal cancer surgery in clinical practice: a single-centre, retrospective study.
Observational study in Blood transfusion = Trasfusione del sangue, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Intravenous iron and iron deficiency anemia in patients with gastrointestinal cancer: A systematic review.PloS one · 2024Pooled it
- Comparison of iron isomaltoside ferumoxytol with iron sucrose for iron deficiency anemia: a meta-analysis of randomized controlled trials.African health sciences · 2023Pooled it
- Platelet-rich plasma for sports-related muscle, tendon and ligament injuries: an umbrella review.Blood transfusion = Trasfusione del sangue · 2019Pooled it
- The use of platelet-rich plasma in oral surgery: a systematic review and meta-analysis.Blood transfusion = Trasfusione del sangue · 2019Pooled it
- Single-dose intravenous ferric carboxymaltose infusion versus multiple fractionated doses of intravenous iron sucrose in the treatment of post-operative anaemia in colorectal cancer patients: a randomised controlled trial.Blood transfusion = Trasfusione del sangue · 2022Trial
- Efficacy of topical tranexamic acid within a blood-saving programme for primary total hip arthroplasty: a pragmatic, open-label randomised study.Blood transfusion = Trasfusione del sangue · 2018Trial
- Iron Deficiency in Athletes.Biological trace element research · 2026Review
- Review
- Postoperative Intravenous Iron Infusion in Anemic Colorectal Cancer Patients: An Observational Study.Biomedicines · 2024Article
- Use and Effectiveness of Carboximaltose Iron in Preoperative Anemia Treatment: A Multicenter and Retrospective Study.Journal of blood medicine · 2024Article
- Review
- Preoperative iron status is a prognosis factor for stage II and III colorectal cancer.International journal of clinical oncology · 2021Article
- Iron and Physical Activity: Bioavailability Enhancers, Properties of Black Pepper (BioperineNutrients · 2020Review
- Intravenous ferric carboxymaltose is effective and safe in patients with inflammatory rheumatic diseases.Blood transfusion = Trasfusione del sangue · 2020Article
- Patient Blood Management: a revolutionary approach to transfusion medicine.Blood transfusion = Trasfusione del sangue · 2019Review
- Implementation of a patient blood management programme in obstetrics: let's do it!Blood transfusion = Trasfusione del sangue · 2019Article
- Article
- The post-operative management of anaemia: more efforts are needed.Blood transfusion = Trasfusione del sangue · 2018Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEvidence on the role of intravenous iron (IVI) supplementation after colorectal cancer (CRC) surgery is rather scant. This study was aimed at assessing the benefit of post-operative IVI administration after elective CRC surgery at our institution. MATERIALS AND
methodsThis was a single-centre, retrospective observational study including all patients who underwent CRC surgery during 2014. Anaemia was defined as a haemoglobin (Hb) <13 g/dL, regardless of gender. Anaemic patients received 200 mg IVI up to three times a week to cover iron deficiency (IVI group). Those who did not receive IVI were placed on standard care (NIVI group). The primary outcome was the proportion of anaemic patients on post-operative day (POD)1 and POD30. Secondary outcomes included Hb changes from POD1 to POD30, transfusion requirements and complication rates.
resultsOf the 159 patients studied, 139 (87%) presented with anaemia: 47 (34%) of these received post-operative IVI and 92 (66%) did not. Patients in the IVI group had lower POD1 Hb levels compared to those in the NIVI group (p=0.001). On POD30, only 103 had their Hb measured (34 IVI, 69 NIVI). Anaemia was more prevalent and more severe among the patients in the IVI group (p=0.027), despite their greater increment in Hb (2.0±1.5 g/dL vs 1.1±1.2 g/dL; p=0.001). Eleven patients needed post-operative transfusions (7 IVI, 4 NIVI; p=0.044). There were no differences in post-operative complication rates between the groups. No IVI-related adverse events were recorded DISCUSSION: Compared with standard care, post-operative IVI administration to anaemic patients improved the recovery of Hb levels at POD30, without increasing post-operative complications.
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