Evidence map›Paper›PMID 29517074›Full record

ArticleCurrent developments in nutrition2017

Influence of Protein Intake, Race, and Age on Responses to a Weight-Reduction Intervention in Obese Women

Connie W Bales, Kathryn N Porter Starr, Melissa C Orenduff, Shelley R McDonald, Karen Molnar, Aubrey K Jarman, Ann Onyenwoke, Hillary Mulder, Martha E Payne, Carl F Pieper

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Current developments in nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02033655 (A High Protein Weight Loss Intervention for Sarcopenic Obesity in Women), which is not on this map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02033655 nacompletednot on this map

A High Protein Weight Loss Intervention for Sarcopenic Obesity in Women

TypeinterventionalSponsorDuke UniversityRan2014 to 2018Enrolled105ConditionsWeight Loss, ObesityArmsProtein supplementation, Diet counseling and group education lessons
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Connie W BalesCenter for the Study of Aging, Duke University Medical Center, Durham, NC.
Kathryn N Porter StarrCenter for the Study of Aging, Duke University Medical Center, Durham, NC.
Melissa C OrenduffCenter for the Study of Aging, Duke University Medical Center, Durham, NC.
Shelley R McDonaldCenter for the Study of Aging, Duke University Medical Center, Durham, NC.
Karen MolnarCenter for the Study of Aging, Duke University Medical Center, Durham, NC.
Aubrey K JarmanCenter for the Study of Aging, Duke University Medical Center, Durham, NC.
Ann OnyenwokeCenter for the Study of Aging, Duke University Medical Center, Durham, NC.
Hillary MulderDepartment of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC.
Martha E PayneOffice of Research Development, Duke University School of Medicine, Durham, NC.
Carl F PieperDepartment of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC.
Duke University · US

Funding

Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI Virginia B Kraus · 2006 to 2026
$24.6M
Interdisciplinary Research Careers in Women's HealthK12HD043446 · NICHD · DUKE UNIVERSITY · PI AMUNDSEN, CINDY · 2002 to 2023
$9.6M
BEHAVIOR AND PHYSIOLOGY IN AGINGT32AG000029 · NIA · DUKE UNIVERSITY · PI Maria Marquine · 1985 to 2026
$9.3M
Nutritional (High Protein) Perihabilitation in Older Veterans Undergoing SurgeryIK2RX002348 · VA · DURHAM VA MEDICAL CENTER · PI STARR, KATHRYN N · 2017 to 2021
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NIA NIH HHS P30 AG028716NIA NIH HHS T32 AG000029NICHD NIH HHS K12 HD043446RRD VA IK2 RX002348
6 · The paper itself

Abstract

backgroundWomen have higher rates of obesity than men and develop more pronounced functional deficits as a result. Yet, little is known about how obesity reduction affects their functional status, including whether their responses differ when protein intake is enhanced.

objectiveThe aim of this study was to confirm the feasibility of delivery of a higher-protein (balanced at each meal) calorie-restricted diet in obese women and determine its efficacy for influencing function and retention of lean mass.

methodObese community-dwelling women [

resultsBoth groups reduced calorie intakes and body weights (

conclusionsA clinically important functional benefit of obesity reduction was confirmed in both study groups, with no significant group effect. Our findings of racial differences in response to the intervention and a potential influence of participant age lend support for further studies sufficiently powered to explore the interaction of race and age with functional responses to obesity reduction in women. This trial was registered at clinicaltrials.gov as NCT02033655.

Indexed as

agebalanced proteinbody compositiondynapenic obesityfunctionracewomen

Identifiers

PMID29517074
PMCPMC5836509
OpenAlexW2606521934

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.