Evidence map›Paper›PMID 29516447›Full record

ArticleRevista de neurologia2018

An agenda for 21st century neurodevelopmental medicine: lessons from autism.

A Klin, W Jones

Open access · greenAbstract read
In one paragraph

Article in Revista de neurologia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Affording autism an early brain development re-definition.Development and psychopathology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

A KlinChildren's Healthcare of Atlanta and Emory University School of Medicine. Atlanta, Georgia, EE.UU.
W JonesChildren's Healthcare of Atlanta and Emory University School of Medicine. Atlanta, Georgia, EE.UU.
Children's Healthcare of Atlanta · US

Funding

The ontogeny of social vocal engagement and its derailment in autismP50MH100029 · NIMH · EMORY UNIVERSITY · PI RAMSAY, GORDON JAMES · 2012 to 2021
$20.1M
Early Quantitative Characterization of Reciprocal Social BehaviorR01HD068479 · NICHD · WASHINGTON UNIVERSITY · PI CONSTANTINO, JOHN N. · 2012 to 2016
$2.7M
The Ontogeny of Social Visual Engagement in Infants at Risk for AutismR01MH083727 · NIMH · YALE UNIVERSITY · PI JONES, WARREN · 2008 to 2012
$2.7M
NICHD NIH HHS R01 HD068479NIMH NIH HHS P50 MH100029NIMH NIH HHS R01 MH083727
6 · The paper itself

Abstract

The future of neurodevelopmental medicine has the potential of situating child neurology at the forefront of a broad-based public health effort to optimize neurodevelopmental outcomes of children born with high-prevalence and diverse genetic, pre- and peri-natal, and environmental burdens compromising early brain development and leading to lifetime disabilities. Building on advancements in developmental social neuroscience and in implementation science, this shift is already occurring in the case of emblematic neurodevelopmental disorders such as autism. Capitalizing on early neuroplasticity and on quantification of trajectories of social-communicative development, new technologies are emerging for high-throughput and cost-effective diagnosis and for community-viable delivery of powerful treatments, in seamless integration across previously fragmented systems of healthcare delivery. These solutions could be deployed in the case of other groups of children at greater risk for autism and communication delays, such as those born extremely premature or with congenital heart disease. The galvanizing concept in this aspirational future is a public health focus on promoting optimal conditions for early brain development, not unlike current campaigns promoting pre-natal care, nutrition or vaccination.

Indexed as

Autistic DisorderDevelopmental DisabilitiesBrainCaregiversChildChild, PreschoolCommunicationForecastingHeart Defects, CongenitalHumansInfantInfant, NewbornInfant, PrematureInfant, Premature, DiseasesInterdisciplinary CommunicationNeuronal Plasticity

Identifiers

PMID29516447
PMCPMC6606044
OpenAlexW2974572568

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.