Evidence map›Paper›PMID 29516246›Full record

ArticleArchives of virology2018

A barnavirus sequence mined from a transcriptome of the Antarctic pearlwort Colobanthus quitensis.

Max L Nibert, Austin R Manny, Humberto J Debat, Andrew E Firth, Laura Bertini, Carla Caruso

Open access · hybridAbstract read
In one paragraph

Article in Archives of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Max L NibertDepartment of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, 02115, USA. mnibert@hms.harvard.edu.
Austin R MannyPh.D. Program in Virology, Harvard University, Cambridge, MA, 02138, USA.
Humberto J DebatInstituto de Patología Vegetal, Centro de Investigaciones Agropecuarias, Instituto Nacional de Tecnología Agropecuaria (IPAVE-CIAP-INTA), X5020ICA, Córdoba, Argentina.
Andrew E FirthDepartment of Pathology, Division of Virology, University of Cambridge, Cambridge, CB2 1QP, UK.
Laura BertiniDepartment of Ecological and Biological Sciences, Universita degli Studi della Tuscia, 01100, Viterbo, Italy.
Carla CarusoDepartment of Ecological and Biological Sciences, Universita degli Studi della Tuscia, 01100, Viterbo, Italy.
Harvard University · USUniversità degli Studi della Tuscia · ITNational Agricultural Technology Institute · ARUniversity of Cambridge · GB

Funding

MOLECULAR BASIS OF VIRAL INFECTIVITYT32AI007245 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Aaron Gregory Schmidt · 1985 to 2026
$11.3M
MICROSCOPY &IMAGE ANALYSIS OF UNSTAINED MACROMOLECULESR01GM033050 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BAKER, TIMOTHY S · 1985 to 2017
$4.3M
NIAID NIH HHS T32 AI007245NIGMS NIH HHS R01 GM033050NIH HHS 2T32AI007245NIH HHS 5R01GM033050Wellcome Trust 106207
6 · The paper itself

Abstract

Because so few viruses in the family Barnaviridae have been reported, we searched for more of them in public sequence databases. Here, we report the complete coding sequence of Colobanthus quitensis associated barnavirus 1, mined from a transcriptome of the Antarctic pearlwort Colobanthus quitensis. The 4.2-kb plus-strand sequence of this virus encompasses four main open reading frames (ORFs), as expected for barnaviruses, including ORFs for a protease-containing polyprotein, an RNA-dependent RNA polymerase whose translation appears to rely on - 1 ribosomal frameshifting, and a capsid protein that is likely to be translated from a subgenomic RNA. The possible derivation of this virus from a fungus associated with C. quitensis is discussed.

Indexed as

Open Reading FramesCapsid ProteinsCaryophyllaceaeDatabases, GeneticData MiningFrameshifting, RibosomalFungiGenome, ViralPlant VirusesRNA-Dependent RNA PolymeraseRNA, ViralRNA VirusesTranscriptomeCapsid ProteinsRNA-Dependent RNA PolymeraseRNA, Viral

Identifiers

PMID29516246
PMCPMC5999160
OpenAlexW2790844670

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.