ArticleRoyal Society open science2018
Multimodal integration and stimulus categorization in putative mushroom body output neurons of the honeybee.
Article in Royal Society open science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 74 citations in OpenAlex.
- Form informs function: innervation patterns of projection neurons correspond to response profiles of mushroom body output neurons during olfactory-visual integration.Frontiers in physiology · 2026Article
- The fru gene specifies male cooperative behaviors in honeybee colonies.Nature communications · 2025Article
- The Pheromone Landscape ofMolecules (Basel, Switzerland) · 2025Review
- Dedicated developmental programing for group-supporting behaviors in eusocial honeybees.Science advances · 2024Article
- Article
- Article
- What do the mushroom bodies do for the insect brain? Twenty-five years of progress.Learning & memory (Cold Spring Harbor, N.Y.) · 2024Article
- Stimulus intensity and temporal configuration interact during bimodal learning and memory in honey bees.PloS one · 2024Article
- Reinforcement learning as a robotics-inspired framework for insect navigation: from spatial representations to neural implementation.Frontiers in computational neuroscience · 2024Article
- The role of learning-walk related multisensory experience in rewiring visual circuits in the desert ant brain.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2023Review
- Visual accelerated and olfactory decelerated responses during multimodal learning in honeybees.Frontiers in physiology · 2023Article
- Minimal circuit motifs for second-order conditioning in the insect mushroom body.Frontiers in physiology · 2023Article
- Honey bees respond to multimodal stimuli following the principle of inverse effectiveness.The Journal of experimental biology · 2022Article
- Review
- Categorizing Visual Information in Subpopulations of Honeybee Mushroom Body Output Neurons.Frontiers in physiology · 2022Article
- Tropilaelaps mercedesae parasitism changes behavior and gene expression in honey bee workers.PLoS pathogens · 2021Article
- Plasticity and modulation of olfactory circuits in insects.Cell and tissue research · 2021Review
- Multi-modal cue integration in the black garden ant.Animal cognition · 2020Article
- Opponent processes in visual memories: A model of attraction and repulsion in navigating insects' mushroom bodies.PLoS computational biology · 2020Article
- Optimality of sparse olfactory representations is not affected by network plasticity.PLoS computational biology · 2020Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Flowers attract pollinating insects like honeybees by sophisticated compositions of olfactory and visual cues. Using honeybees as a model to study olfactory-visual integration at the neuronal level, we focused on mushroom body (MB) output neurons (MBON). From a neuronal circuit perspective, MBONs represent a prominent level of sensory-modality convergence in the insect brain. We established an experimental design allowing electrophysiological characterization of olfactory, visual, as well as olfactory-visual induced activation of individual MBONs. Despite the obvious convergence of olfactory and visual pathways in the MB, we found numerous unimodal MBONs. However, a substantial proportion of MBONs (32%) responded to both modalities and thus integrated olfactory-visual information across MB input layers. In these neurons, representation of the olfactory-visual compound was significantly increased compared with that of single components, suggesting an additive, but nonlinear integration. Population analyses of olfactory-visual MBONs revealed three categories: (i) olfactory, (ii) visual and (iii) olfactory-visual compound stimuli. Interestingly, no significant differentiation was apparent regarding different stimulus qualities within these categories. We conclude that encoding of stimulus quality within a modality is largely completed at the level of MB input, and information at the MB output is integrated across modalities to efficiently categorize sensory information for downstream behavioural decision processing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.