Evidence map›Paper›PMID 29515797›Full record

ArticleOncotarget2018

Hinrich Wieder, Ambros J Beer, Jens Siveke, Tibor Schuster, Andreas K Buck, Ken Herrmann, Jens C Stollfuss

Abstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  3. Review
  4. Pancreatic Ductal Adenocarcinoma: The Dawn of the Era of Nuclear Medicine?International journal of molecular sciences · 2021
    Review
  5. Review
  6. Translational molecular imaging in exocrine pancreatic cancer.European journal of nuclear medicine and molecular imaging · 2018
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hinrich WiederDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität, München, Munich, Germany.
Ambros J BeerDepartment of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität, München, Munich, Germany.
Jens SivekeDivision of Solid Tumor Translational Oncology, German Cancer Consortium, Partner Site Essen, Universitätsklinikum Essen, Essen, Germany.
Tibor SchusterDepartment of Family Medicine, McGill University, Montreal, Quebec, Canada.
Andreas K BuckDepartment of Nuclear Medicine, University of Würzburg, Würzburg, Germany.
Ken HerrmannDepartment of Nuclear Medicine, Universitätsklinikum Essen, Essen, Germany.
Jens C StollfussInstitute for Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to correlate preoperative 3'-deoxy-3'-[ MATERIALS AND

methodsWe performed a prospective analysis in 27 patients with adenocarcinoma of the pancreas (15 males, 12 females, mean age: 62 ± 13 years, range: 34 - 86 years). FLT PET (45 min p.i., 300 MBq FLT; ECAT HR+) images were acquired according to standard protocols. FLT uptake was quantified using standardised uptake values (SUV). Mean follow-up was 35 months (range 24-49). FLT uptake was correlated with survival using Martingale residual analysis.

resultsTwenty-two patients died during follow-up. Mean overall survival was 18.8 months (SD: 12.7 months, 95% CI: 7.7, 26.5). FLT PET showed a mean SUV of 2.5 (range: 1.1 - 6.5). Martingale residual analysis revealed significant correlation between survival and FLT uptake (

conclusionsFLT PET allows risk stratification for death in patients with resectable pancreatic cancer prior to surgery.

Indexed as

FLToutcome prognosispancreasPETpredictive value

Identifiers

PMID29515797
PMCPMC5839378

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.