Evidence map›Paper›PMID 29515653›Full record

ArticleEcancermedicalscience2018

MGMT promoter methylation in Peruvian patients with glioblastoma.

Carolina Belmar-Lopez, Carlos A Castaneda, Miluska Castillo, Pamela García-Corrochano, Enrique Orrego, Barbara Meléndez, Sandro Casavilca, Claudio Flores, Enrique Orrego

Open access · goldAbstract read
In one paragraph

Article in Ecancermedicalscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Carolina Belmar-LopezDepartment of Research, Instituto Nacional de Enfermedades Neoplasicas. Av Angamos Este 2520, Surquillo, Lima 15038, Peru.
Carlos A CastanedaDepartment of Research, Instituto Nacional de Enfermedades Neoplasicas. Av Angamos Este 2520, Surquillo, Lima 15038, Peru.
Miluska CastilloDepartment of Research, Instituto Nacional de Enfermedades Neoplasicas. Av Angamos Este 2520, Surquillo, Lima 15038, Peru.
Pamela García-CorrochanoDepartment of Neurosurgery, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Enrique OrregoDepartment of Neurosurgery, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Barbara MeléndezMolecular Pathology Research Unit, Department of Pathology, Virgen de la Salud Hospital. Av De Barber s/n, Toledo 45005, Spain.
Sandro CasavilcaDepartment of Pathology, Instituto Nacional de Enfermedades Neoplasicas. Av Angamos Este 2520, Surquillo, Lima 15038, Peru.
Claudio FloresDepartment of Research, Oncosalud. Av Guardia Civil 571, San Borja, Lima 15036, Peru.
Enrique OrregoDepartment of Neurosurgery, Instituto Nacional de Enfermedades Neoplasicas, Lima 15038, Peru.
Instituto Nacional de Enfermedades Neoplásicas · PEHospital Virgen de la Salud · ESUniversidad Privada San Juan Bautista · PE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeO PATIENTS AND

methodsWe evaluated retrospectively 50 cases of resected glioblastoma during the period 2008-2013 at Instituto Nacional de Enfermedades Neoplasicas in Peru. Samples consisted of paraffin embedded and frozen tumour tissue.

resultsUnmethylated, methylated and partially methylated statuses were found in 54%, 20% and 26% of paraffin-embedded samples, respectively. Methylation status was confirmed in the Virgen de la Salud Hospital and frozen samples. There was an association between the status of

conclusion

Indexed as

glioblastomaLatin AmericanmethylationMGMT

Identifiers

PMID29515653
PMCPMC5834313
OpenAlexW2793867253

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.