Evidence map›Paper›PMID 29515645›Full record

ArticleWorld journal of emergency surgery : WJES2018

Evaluation of capillary leakage after vasopressin resuscitation in a hemorrhagic shock model.

Roberto Bini, Osvaldo Chiara, Stefania Cimbanassi, Giorgio Olivero, Antonella Trombetta, Paolo Cotogni

Open access · goldAbstract read
In one paragraph

Article in World journal of emergency surgery : WJES, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Roberto Bini1Department of Surgery, S. Giovanni Bosco Hospital, Turin, Italy.
Osvaldo Chiara2Trauma Center and Metropolitan Trauma Network Department, Niguarda Hospital, Milan, Italy.
Stefania Cimbanassi2Trauma Center and Metropolitan Trauma Network Department, Niguarda Hospital, Milan, Italy.
Giorgio Olivero3Department of Surgical Sciences, S. Giovanni Battista Hospital, University of Turin, Turin, Italy.
Antonella Trombetta4Department of Medical Sciences, University of Turin, Turin, Italy.
Paolo Cotogni5Department of Anesthesia and Intensive Care, S. Giovanni Battista Hospital, University of Turin, Via Giovanni Giolitti 9, 10123 Turin, Italy.ORCID 0000-0002-4930-8984
Azienda Ospedaliero Universitaria San Giovanni Battista · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITOspedale San Giovanni Bosco · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hemorrhagic shock (HS) is a major threat to patients with trauma and spontaneous bleeding. The aim of the study was to investigate early effects of vasopressin on metabolic and hemodynamic parameters and endothelium permeability by measuring capillary leakage compared to those of other resuscitation strategies in a HS model. Methods: Forty-five Sprague-Dawley rats were randomized into five groups: S group ( Results: In the vasopressin group, the MAP was higher than in the RL and RLB groups ( Conclusion: Although vasopressin was proposed as a vasoactive drug for provisional hemodynamic optimization in the early phase of HS resuscitation, the overall findings of this experimental study focus on the possible critical side effects of vasopressin on metabolic parameters and endothelium permeability.

Indexed as

AnimalsArterial PressureCapillary Leak SyndromeCapillary PermeabilityLungRatsRats, Sprague-DawleyResuscitationShock, HemorrhagicVasopressinsVasopressinsArginine vasopressinHemorrhageShock treatmentVasopressors

Identifiers

PMID29515645
PMCPMC5836391
OpenAlexW2802267888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.