Evidence map›Paper›PMID 29515622›Full record

ArticleDementia and geriatric cognitive disorders extra

High Incidence of Sporadic Creutzfeldt-Jakob Disease in Slovenia in 2015: A Case Series.

Tomaž Rus, Bogdan Lorber, Maja Trošt, Srečko Dobrecovič, Nuška Čakš Jager, Mara Popović, Milica G Kramberger

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Article in Dementia and geriatric cognitive disorders extra. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Review
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  9. Creutzfeldt-Jakob disease: A case report.Caspian journal of internal medicine · 2021
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Tomaž RusaDepartment of Neurology, Ljubljana University Medical Centre, Ljubljana, Slovenia.
Bogdan LorberaDepartment of Neurology, Ljubljana University Medical Centre, Ljubljana, Slovenia.
Maja TroštaDepartment of Neurology, Ljubljana University Medical Centre, Ljubljana, Slovenia.
Srečko DobrecovičbInstitute of Radiology, Ljubljana University Medical Centre, Ljubljana, Slovenia.
Nuška Čakš JagercNational Institute of Public Health, Ljubljana, Slovenia.
Mara PopovićdInstitute of Pathology, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia.
Milica G KrambergeraDepartment of Neurology, Ljubljana University Medical Centre, Ljubljana, Slovenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCreutzfeldt-Jakob disease (CJD) is a rare fatal neurodegenerative disorder presenting with rapid cognitive decline and additional signs. The clinical characteristics of an increasing number of sporadic CJD (sCJD) patients admitted to the Ljubljana University Medical Centre are presented as well as the incidence of sCJD in Slovenia in 2015 compared to previous years.

methodsWe investigated patients presenting with rapidly progressive dementia and at least one additional sign. The diagnosis was made based on clinical diagnostic criteria and an autopsy was performed in all cases. Data on definite sCJD cases in Slovenia since 1999 were obtained and its incidence was calculated.

resultsEight patients with definite sCJD died in 2015 in Slovenia (incidence: 3.89 cases per million). The long-term incidence 1999 was 1.67 per million.

conclusionsThe incidence of sCJD was considerably higher in 2015. It reflects fluctuations in sporadic cases of this rare disease. The rising trend might indicate a previous underestimation and better recognition of the disease.

Indexed as

Case seriesIncidenceSporadic Creutzfeldt-Jakob disease

Identifiers

PMID29515622
PMCPMC5836161

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.