Evidence map›Paper›PMID 29515594›Full record

ArticleFrontiers in immunology2018

Mammalian Target of Rapamycin Inhibition in

Jorge David Rojas Márquez, Yamile Ana, Ruth Eliana Baigorrí, Cinthia Carolina Stempin, Fabio Marcelo Cerban

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Guideline
  2. Comparative 5' IsomiRome Analysis Uncovers Dysregulated 5' IsomiRs inComputational and structural biotechnology journal · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Transcriptomic Profile of Canine DH82 Macrophages Infected byInternational journal of molecular sciences · 2022
    Article
  11. Article
  12. Review
  13. Gasdermins in Innate Host Defense AgainstFrontiers in immunology · 2022
    Review
  14. Induction of Autophagy by Ursolic Acid Promotes the Elimination ofFrontiers in cellular and infection microbiology · 2022
    Article
  15. Article
  16. Mitochondria as a Cellular Hub in Infection and Inflammation.International journal of molecular sciences · 2021
    Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jorge David Rojas MárquezFacultad de Ciencias Químicas, Universidad Nacional de Córdoba (UNC), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, Argentina.
Yamile AnaFacultad de Ciencias Químicas, Universidad Nacional de Córdoba (UNC), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, Argentina.
Ruth Eliana BaigorríFacultad de Ciencias Químicas, Universidad Nacional de Córdoba (UNC), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, Argentina.
Cinthia Carolina StempinFacultad de Ciencias Químicas, Universidad Nacional de Córdoba (UNC), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, Argentina.
Fabio Marcelo CerbanFacultad de Ciencias Químicas, Universidad Nacional de Córdoba (UNC), Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, Argentina.
Universidad Nacional de Córdoba · ARConsejo Nacional de Investigaciones Científicas y Técnicas · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The causative agent of Chagas' disease,

Indexed as

AnimalsChagas DiseaseCytokinesIndoleamine-Pyrrole 2,3,-DioxygenaseInflammasomesMacrophagesMiceMice, Inbred BALB CMice, KnockoutNitric Oxide Synthase Type IINLR Family, Pyrin Domain-Containing 3 ProteinReactive Oxygen SpeciesSirolimusTOR Serine-Threonine KinasesTrypanosoma cruziCytokinesIndoleamine-Pyrrole 2,3,-DioxygenaseInflammasomesmTOR protein, mouseNitric Oxide Synthase Type IINLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseNos2 protein, mouseReactive Oxygen SpeciesSirolimusTOR Serine-Threonine Kinasesmacrophagemammalian target of rapamycinNLRP3reactive oxygen speciesTrypanosoma cruzi

Identifiers

PMID29515594
PMCPMC5826284
OpenAlexW2789603153

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.