ArticleFrontiers in immunology2018
Human Intestinal Epithelial Cells Release Antiviral Factors That Inhibit HIV Infection of Macrophages.
Abstract read
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Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed.
- Cellular miR-24-3p inhibits vaccinia virus replication by targeting kinesin-like protein KIF21B.Biosafety and health · 2026Article
- Therapeutic Potential of Extracellular Vesicles: From Biogenesis, Isolation and Molecular Characterization to Addressing Translational Gaps and Regulatory Barriers.International journal of molecular sciences · 2026Review
- Pharmacological and genetic modulation of IL-32 expression in intestinal epithelial cells does not impact HIV-1 outgrowth in co-cultured CD4Frontiers in immunology · 2026Article
- Analysis of the profiles of human endogenous retroviruses W, K, and H and the systemic inflammatory status in vitiligo patients: insights on the dynamics of endogenous retroviral expression and its interplay with inflammatory response.Frontiers in cellular and infection microbiology · 2026Article
- Activation of cytosolic DNA sensing in NCM460 intestinal epithelial cells induces antiviral factors that restrict HIV infection in macrophages.Frontiers in immunology · 2026Article
- TLR3 activation of microglia-containing cerebral organoid induces antiviral factors against HIV-1 infection.Frontiers in pharmacology · 2026Article
- Guanylate-binding protein 5: a promising biomarker and therapeutic target.Infection and immunity · 2025Review
- Unveiling the promise: Exosomes as game-changers in anti-infective therapy.Exploration (Beijing, China) · 2024Review
- From stem cells to extracellular vesicles: a new horizon in tissue engineering and regenerative medicine.Cytotechnology · 2024Review
- Flagellin Restricts HIV-1 Infection of Macrophages through Modulation of Viral Entry Receptors and CC Chemokines.Viruses · 2024Article
- The Role of Extracellular Vesicles in Pandemic Viral Infections.Journal of microbiology (Seoul, Korea) · 2024Review
- Extracellular vesicles as tools and targets in therapy for diseases.Signal transduction and targeted therapy · 2024Review
- Involvement of Embryo-Derived and Monocyte-Derived Intestinal Macrophages in the Pathogenesis of Inflammatory Bowel Disease and Their Prospects as Therapeutic Targets.International journal of molecular sciences · 2024Review
- Activation of Toll-like receptor 3 inhibits HIV infection of human iPSC-derived microglia.Journal of medical virology · 2023Article
- MicroRNAs: Small but Key Players in Viral Infections and Immune Responses to Viral Pathogens.Biology · 2023Review
- The complex role of extracellular vesicles in HIV infection.BMB reports · 2023Review
- The Gut Microbiome During Pregnancy.Maternal-fetal medicine (Wolters Kluwer Health, Inc.) · 2023Article
- Exosome and virus infection.Frontiers in immunology · 2023Review
- Consequences of HIV infection in the bone marrow niche.Frontiers in immunology · 2023Review
- Intestinal Immune Imbalance is an Alarm in the Development of IBD.Mediators of inflammation · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Le GuoWuhan University School of Basic Medical Sciences, Wuhan, China.
Xi-Qiu XuWuhan University School of Basic Medical Sciences, Wuhan, China.
Li ZhouWuhan University School of Basic Medical Sciences, Wuhan, China.
Run-Hong ZhouWuhan University School of Basic Medical Sciences, Wuhan, China.
Xu WangDepartment of Pathology and Laboratory Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States.
Jie-Liang LiDepartment of Pathology and Laboratory Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, United States.
Jin-Biao LiuWuhan University School of Basic Medical Sciences, Wuhan, China.
Hang LiuWuhan University School of Basic Medical Sciences, Wuhan, China.
Biao ZhangWuhan University School of Basic Medical Sciences, Wuhan, China.
Wen-Zhe HoWuhan University School of Basic Medical Sciences, Wuhan, China.
Funding
Opioids, HIV/HCV and Host Cell Innate ImmunityR01DA022177 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI HO, WENZHE · 2007 to 2017
$2.9MRole of miRNAs in Methamphetamine/HIV-mediated Immune ActivationR01DA045568 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI HO, WENZHE · 2018 to 2022
$2.0MMethamphetamine, Innate Immunity and HIVR01DA041302 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI HO, WENZHE · 2016 to 2020
$1.8MOpioids, Extracellular Vesicles and BBB Innate ImmunityR21DA042373 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI HO, WENZHE · 2017 to 2018
$436kRole of Exosomes in the Crosstalk Between Brain Endothelium and HIV NeuroinvasionR21MH109385 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI LI, JIELIANG · 2016 to 2017
$429kExosome in Methamphetamine and HIV-associated NeurodegenerationR21DA040329 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI LI, JIELIANG · 2015 to 2016
$427kNIDA NIH HHS R01 DA022177NIDA NIH HHS R01 DA041302NIDA NIH HHS R21 DA040329NIDA NIH HHS R21 DA042373NIMH NIH HHS R21 MH109385
Abstract
As a rich source of CD4
Indexed as
AgedCell LineChemokines, CCEpithelial CellsExosomesHIV-1HIV InfectionsHumansImmunity, InnateInterferon Regulatory FactorsInterferonsIntestinal MucosaMacrophagesMaleToll-Like Receptor 3Chemokines, CCInterferon Regulatory FactorsInterferonsTLR3 protein, humanToll-Like Receptor 3exosomesHIVhuman intestinal epithelial cellsIFN-stimulated genesinterferonsmacrophagestoll-like receptor 3
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.