Evidence map›Paper›PMID 29515567›Full record

ArticleFrontiers in immunology2018

Interorgan Molecular Communication Strategies of "Local" and "Systemic" Innate Immune Responses in Mosquito

Tanwee Das De, Punita Sharma, Tina Thomas, Deepak Singla, Sanjay Tevatiya, Seena Kumari, Charu Chauhan, Jyoti Rani, Vartika Srivastava, Ramandeep Kaur and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 57 citations in OpenAlex.

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  7. Differential expression of immunity-related genes in larvalFrontiers in cellular and infection microbiology · 2023
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  10. RETRACTED: Curcumin-InjectedMolecules (Basel, Switzerland) · 2022
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  14. Genetic changes ofCurrent research in immunology · 2021
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  15. Trained Immunity inFrontiers in microbiology · 2021
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  16. Article
  17. Altered Gut Microbiota and Immunity DefinesFrontiers in immunology · 2020
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  18. Listening to your gut: immune challenge to the gut sensitizes body wall nociception in the caterpillarPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Article
  19. Female bed bugs (Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Tanwee Das DeHost-Parasite Interaction Biology Group, ICMR-National Institute of Malaria Research, New Delhi, India.
Punita SharmaHost-Parasite Interaction Biology Group, ICMR-National Institute of Malaria Research, New Delhi, India.
Tina ThomasHost-Parasite Interaction Biology Group, ICMR-National Institute of Malaria Research, New Delhi, India.
Deepak SinglaHost-Parasite Interaction Biology Group, ICMR-National Institute of Malaria Research, New Delhi, India.
Sanjay TevatiyaHost-Parasite Interaction Biology Group, ICMR-National Institute of Malaria Research, New Delhi, India.
Seena KumariHost-Parasite Interaction Biology Group, ICMR-National Institute of Malaria Research, New Delhi, India.
Charu ChauhanHost-Parasite Interaction Biology Group, ICMR-National Institute of Malaria Research, New Delhi, India.
Jyoti RaniHost-Parasite Interaction Biology Group, ICMR-National Institute of Malaria Research, New Delhi, India.
Vartika SrivastavaHost-Parasite Interaction Biology Group, ICMR-National Institute of Malaria Research, New Delhi, India.
Ramandeep KaurHost-Parasite Interaction Biology Group, ICMR-National Institute of Malaria Research, New Delhi, India.
Kailash C PandeyDepartment of Biochemistry, National Institute for Research in Environmental Health, Indian Council of Medical Research, Bhopal, India.
Rajnikant DixitHost-Parasite Interaction Biology Group, ICMR-National Institute of Malaria Research, New Delhi, India.
National Institute of Malaria Research · INDepartment of Biotechnology · INIndian Council of Medical Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mosquitoes that transmit many deadly infectious diseases also need to keep fighting against many microbial infections. Constitutive expression of multiple antimicrobial peptides (AMPs) in almost all body tissues is believed to facilitate the effective management of these local infections. When any infection breaches the local barrier, AMPs are induced rapidly in non-target tissues such as hemocytes (HCs) and establish their co-ordination with systemic immune effectors to clear off the body infection. But how interorgan immune communication is managed during local and systemic infections remain largely unknown. To understand this interorgan molecular relationship, we identified, extensively profiled and compared the expression of AMPs in three important mosquito tissues

Indexed as

Immunity, InnateAnimalsAnophelesBacillus subtilisEscherichia coliEscherichia coli InfectionsFat BodyFemaleGram-Positive Bacterial InfectionsHemocytesIntestinesReactive Oxygen SpeciesReactive Oxygen Speciesantimicrobial peptidefat bodyhemocyteinnate immunitymidgutmosquito

Identifiers

PMID29515567
PMCPMC5826171
OpenAlexW2793957650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.