Evidence map›Paper›PMID 29515376›Full record

ArticleFrontiers in neuroanatomy2018

Cerebral Artery Diameter in Inbred Mice Varies as a Function of Strain.

Baogang Qian, Robert F Rudy, Tianxi Cai, Rose Du

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroanatomy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

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  8. Ocular Ischemic Syndrome and Its Related Experimental Models.International journal of molecular sciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Baogang QianDepartment of Neurosurgery, Brigham and Women's Hospital, Boston, MA, United States.
Robert F RudyDepartment of Neurosurgery, Brigham and Women's Hospital, Boston, MA, United States.
Tianxi CaiBiostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, United States.
Rose DuDepartment of Neurosurgery, Brigham and Women's Hospital, Boston, MA, United States.
Harvard University · USBrigham and Women's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many strains of mice are utilized in mouse models of cerebrovascular diseases. Variations in vascular anatomy between these strains has been documented and may influence the phenotype in stroke models. To address inter-strain variations in the circle of Willis anatomy, the diameters of internal carotid, posterior communicating, anterior cerebral, and middle cerebral arteries in 144 mice from 32 inbred strains were measured. Arterial diameters were analyzed as a function of animal weight, age, and strain. Variations in the structure of the circle of Willis across strains were observed and noted. While right-sided anterior cerebral arteries were significantly greater in diameter than their left-sided counterparts across most strains, variations in arterial diameter are strain specific. Adult mouse weight was not found to be associated with arterial diameter across strains, suggesting that cerebral artery size is associated with strain independently of weight. This study demonstrates strain dependent variations in the murine circle of Willis, which should be taken into consideration when studying mouse models of cerebrovascular diseases.

Indexed as

cerebral arterycerebral circulationmouse strainvariant anatomyvascular anatomy

Identifiers

PMID29515376
PMCPMC5826213
OpenAlexW2792522625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.