ArticleInternational journal of obesity (2005)2018
Association between body mass index and laboratory-confirmed influenza in middle aged and older adults: a prospective cohort study.
Article in International journal of obesity (2005), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04267809 (Modulating Endoplasmic Reticulum Stress as a Prophylactic Approach Against Symptomatic Viral Infection), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Modulating Endoplasmic Reticulum Stress as a Prophylactic Approach Against Symptomatic Viral Infection
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Obesity Increases the Severity and Mortality of Influenza and COVID-19: A Systematic Review and Meta-Analysis.Frontiers in endocrinology · 2020Pooled it
- Elevated body mass index is not significantly associated with reduced influenza vaccine effectiveness.Scientific reports · 2024Article
- Risk Factors for COVID-19 and Respiratory Tract Infections during the Coronavirus Pandemic.Vaccines · 2024Article
- The TIGITScientific reports · 2023Article
- Association between obesity and COVID-19 mortality and length of stay in intensive care unit patients in Brazil: a retrospective cohort study.Scientific reports · 2022Article
- Association between visceral fat and influenza infection in Japanese adults: A population-based cross-sectional study.PloS one · 2022Article
- Obesity Is Associated With Increased Susceptibility to Influenza A (H1N1pdm) but Not H3N2 Infection.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Longitudinal Assessment of Immune Responses to Repeated Annual Influenza Vaccination in a Human Cohort of Adults and Teenagers.Frontiers in immunology · 2021Article
- The Weight of Obesity in Immunity from Influenza to COVID-19.Frontiers in cellular and infection microbiology · 2021Review
- The obesity paradox: Analysis from the SMAtteo COvid-19 REgistry (SMACORE) cohort.Nutrition, metabolism, and cardiovascular diseases : NMCD · 2020Article
- Article
- David Versus Goliath: The Clinical Consequences of an Influenza A Viral Infection in an Unvaccinated Patient.Cureus · 2019Article
- Influenza Pathogenesis: The Effect of Host Factors on Severity of Disease.Journal of immunology (Baltimore, Md. : 1950) · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies conducted during the 2009 influenza A (H1N1) pandemic found that obesity increases the risk of severe influenza including hospitalization and death. In this study, we examined the relationship of BMI with having laboratory-confirmed seasonal influenza and influenza-related respiratory hospitalization.
methodsWe linked a cohort of 246,494 adults aged ≥45 years with data on BMI to subsequent laboratory-confirmed influenza notifications and cause-specific hospitalizations from 2006 to 2015. Cox-proportional hazard models were used to estimate the risk of incident laboratory-confirmed influenza and influenza-related respiratory hospitalizations according to BMI, adjusting for age, sex and other covariates.
resultsAfter 1,840,408 person-years of follow-up, 1891 participants had laboratory-confirmed influenza notifications (crude rate 10.3/10,000 person-years) of whom 623 were hospitalized for a respiratory illness. Compared to those with healthy BMI (22.5 to <25.0 kg/m
conclusionsOur results suggest that obese adults have a similar risk of hospitalization for seasonal influenza as adults with cardiovascular disease and diabetes, and should therefore be equally prioritized for funded interventions such as targeted immunization programs.
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Registered trials
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