ArticleThe ISME journal2018
Comparative genomics sheds light on niche differentiation and the evolutionary history of comammox Nitrospira.
Article in The ISME journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
82 citing papers in PubMed, 358 citations in OpenAlex.
- Asynchronous recovery of canonical ammonia oxidizers and comammox drives post-drought NWorld journal of microbiology & biotechnology · 2026Article
- Gradual COEnvironmental microbiology · 2026Article
- Article
- Water flow shapes the niche differentiation of complete ammonia oxidizers in sediments.Archives of microbiology · 2026Article
- Unique phylogenies and metabolic adaptations of novel lineage III and comammoxISME communications · 2026Article
- Metabolic potential and contributions of ammonia-oxidizing microorganisms and complete ammonia oxidizers to soil nitrification in upland soils of northern China.ISME communications · 2026Article
- Seagrass-derived carbon suppresses nitrification and NISME communications · 2026Article
- Unique characteristics of acid-tolerant comammox bacteria revealed by multi-omics analyses.ISME communications · 2026Article
- Ubiquity and Dominance of Comammox Over AOB and AOA and their Links To ARGs in Antarctic Lake Sediments.Microbial ecology · 2025Article
- Microbial diversity supports nitrification: insights from a full-scale anoxic/oxic wastewater treatment process.Applied and environmental microbiology · 2025Article
- Monitoring complete ammonia oxidizers bacteria: relevant players for nitrogen removal from wastewater.AMB Express · 2025Article
- High diversity of nitrifying bacteria and archaea in biofilms from a subsea tunnel.FEMS microbiology ecology · 2025Article
- Functional redundancy and niche complementarity maintain nitrification stability in rapid sand filters.Frontiers in microbiology · 2025Article
- Comprehensive evaluation of primer pairs targeting the ammonia monooxygenase subunit A gene of complete ammonia-oxidizingMicrobiology spectrum · 2024Article
- Metatranscriptomic Analysis Reveals Synergistic Activities of Comammox and Anammox Bacteria in Full-Scale Attached Growth Nitrogen Removal System.Environmental science & technology · 2024Article
- Article
- Dating Ammonia-Oxidizing Bacteria with Abundant Eukaryotic Fossils.Molecular biology and evolution · 2024Article
- Nitrogen source influences the interactions of comammox bacteria with aerobic nitrifiers.Microbiology spectrum · 2024Article
- Unveiling unique microbial nitrogen cycling and nitrification driver in coastal Antarctica.Nature communications · 2024Article
- Biofilm colonization and succession in a full-scale partial nitritation-anammox moving bed biofilm reactor.Microbiome · 2024Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The description of comammox Nitrospira spp., performing complete ammonia-to-nitrate oxidation, and their co-occurrence with canonical β-proteobacterial ammonia oxidizing bacteria (β-AOB) in the environment, calls into question the metabolic potential of comammox Nitrospira and the evolutionary history of their ammonia oxidation pathway. We report four new comammox Nitrospira genomes, constituting two novel species, and the first comparative genomic analysis on comammox Nitrospira. Unlike canonical Nitrospira, comammox Nitrospira genomes lack genes for assimilatory nitrite reduction, suggesting that they have lost the potential to use external nitrite nitrogen sources. By contrast, compared to canonical Nitrospira, comammox Nitrospira harbor a higher diversity of urea transporters and copper homeostasis genes and lack cyanate hydratase genes. Additionally, the two comammox clades differ in their ammonium uptake systems. Contrary to β-AOB, comammox Nitrospira genomes have single copies of the two central ammonia oxidation pathway operons. Similar to ammonia oxidizing archaea and some oligotrophic AOB strains, they lack genes involved in nitric oxide reduction. Furthermore, comammox Nitrospira genomes encode genes that might allow efficient growth at low oxygen concentrations. Regarding the evolutionary history of comammox Nitrospira, our analyses indicate that several genes belonging to the ammonia oxidation pathway could have been laterally transferred from β-AOB to comammox Nitrospira. We postulate that the absence of comammox genes in other sublineage II Nitrospira genomes is the result of subsequent loss.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.