Evidence map›Paper›PMID 29514978›Full record

ReviewThe Journal of biological chemistry2018

Spatiotemporal compartmentalization of hepatic NADH and NADPH metabolism.

Russell P Goodman, Sarah E Calvo, Vamsi K Mootha

Open access · hybridAbstract readReview
In one paragraph

Review in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 137 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Cooperative Architecture of Mitochondrial Proteome Homeostasis.medRxiv : the preprint server for health sciences · 2026
    Article
  9. Article
  10. Article
  11. Changes in the brain [NADFrontiers in aging neuroscience · 2026
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Significance of Malic Enzyme 1 in Cancer: A Review.Current issues in molecular biology · 2025
    Review
  20. Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Russell P GoodmanFrom the Division of Gastroenterology and rpgoodman@mgh.harvard.edu.
Sarah E CalvoHoward Hughes Medical Institute, and Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114 and.
Vamsi K MoothaHoward Hughes Medical Institute, and Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114 and vamsi@hms.harvard.edu.
Howard Hughes Medical Institute · USMassachusetts General Hospital · US

Funding

Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1991 to 2026
$35.3M
NIDDK NIH HHS P30 DK043351
6 · The paper itself

Abstract

Compartmentalization is a fundamental design principle of eukaryotic metabolism. Here, we review the compartmentalization of NAD

Indexed as

Energy MetabolismMetabolic Networks and PathwaysAnimalsCytosolHomeostasisHumansLiverMitochondriaNADNADPOxidation-ReductionOxidative StressSpatio-Temporal AnalysisNADNADPcell metabolismhepatic metabolismhepatocyteintermediary metabolismliverliver metabolismNAD biosynthesisNAD(P)omenicotinamide adenine dinucleotide (NAD)nicotinamide adenine dinucleotide (NADH)oxidation-reduction (redox)

Identifiers

PMID29514978
PMCPMC5961030
OpenAlexW2793048431

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.