Evidence map›Paper›PMID 29514959›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Crystal structure of bacterial succinate:quinone oxidoreductase flavoprotein SdhA in complex with its assembly factor SdhE.

Megan J Maher, Anuradha S Herath, Saumya R Udagedara, David A Dougan, Kaye N Truscott

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. The coenzyme BMicrobial cell (Graz, Austria) · 2023
    Article
  4. Review
  5. Article
  6. Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  7. Mitochondrial complex II and reactive oxygen species in disease and therapy.Redox report : communications in free radical research · 2020
    Review
  8. Review
  9. The roles of SDHAF2 and dicarboxylate in covalent flavinylation of SDHA, the human complex II flavoprotein.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  10. Article
  11. Article
  12. Maturation of the respiratory complex II flavoprotein.Current opinion in structural biology · 2019
    Review
  13. The assembly of succinate dehydrogenase: a key enzyme in bioenergetics.Cellular and molecular life sciences : CMLS · 2019
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Megan J MaherDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC 3086, Australia m.maher@latrobe.edu.au k.truscott@latrobe.edu.au.
Anuradha S HerathDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC 3086, Australia.
Saumya R UdagedaraDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC 3086, Australia.
David A DouganDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC 3086, Australia.ORCID 0000-0001-9313-1904
Kaye N TruscottDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC 3086, Australia m.maher@latrobe.edu.au k.truscott@latrobe.edu.au.
La Trobe University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Succinate:quinone oxidoreductase (SQR) functions in energy metabolism, coupling the tricarboxylic acid cycle and electron transport chain in bacteria and mitochondria. The biogenesis of flavinylated SdhA, the catalytic subunit of SQR, is assisted by a highly conserved assembly factor termed SdhE in bacteria via an unknown mechanism. By using X-ray crystallography, we have solved the structure of

Indexed as

Bacterial ProteinsCrystallizationCrystallography, X-RayElectron Transport Complex IIEscherichia coliEscherichia coli ProteinsFlavoproteinsModels, MolecularProtein BindingProtein ConformationProtein DomainsStrobilurinsBacterial ProteinsElectron Transport Complex IIenestroburinEscherichia coli ProteinsFlavoproteinsSdhA protein, BacteriaSdhE protein, E coliStrobilurinsassemblyflavinylationSdhASdhEstructure

Identifiers

PMID29514959
PMCPMC5866609
OpenAlexW2791860947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.