Evidence map›Paper›PMID 29514842›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2018

Enhanced Intratumoral Delivery of SN38 as a Tocopherol Oxyacetate Prodrug Using Nanoparticles in a Neuroblastoma Xenograft Model.

Ferro Nguyen, Ivan Alferiev, Peng Guan, David T Guerrero, Venkatadri Kolla, Ganesh S Moorthy, Michael Chorny, Garrett M Brodeur

Open access · bronzeAbstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Research Progress of SN38 Drug Delivery System in Cancer Treatment.International journal of nanomedicine · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. A High-Content Screen for C/EBPα Expression Identifies Novel Therapeutic Agents in Dedifferentiated Liposarcoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ferro NguyenDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Ivan AlferievDivision of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Peng GuanDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
David T GuerreroDivision of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Venkatadri KollaDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Ganesh S MoorthyDepartment of Anesthesiology and Critical Care, University of Pennsylvania/Perelman School of Medicine, Philadelphia, Pennsylvania.
Michael ChornyDivision of Cardiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Garrett M BrodeurDivision of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Brodeur@email.chop.edu.
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · US

Funding

Pediatric Scholars ProgramK12HD043245 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI ST. GEME, JOSEPH W. · 2003 to 2022
$7.4M
NICHD NIH HHS K12 HD043245
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug Delivery SystemsNanoparticlesAnimalsAntineoplastic AgentsCell Line, TumorDisease Models, AnimalHumansInjections, IntralesionalIrinotecanMiceNeuroblastomaProdrugsRecurrenceRetreatmentSurvival RateTissue DistributionAntineoplastic AgentsIrinotecanProdrugsTocopherols

Identifiers

PMID29514842
PMCPMC7324957
OpenAlexW2792870535

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.