Evidence map›Paper›PMID 29514804›Full record

ArticleJournal of the American Heart Association2018

Patient and Caregiver Determinants of Patient Quality of Life and Caregiver Strain in Left Ventricular Assist Device Therapy.

Julie T Bidwell, Karen S Lyons, James O Mudd, Kathleen L Grady, Jill M Gelow, Shirin O Hiatt, Christopher V Chien, Christopher S Lee

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Longitudinal changes in physical and psychological outcomes in spousal vs. non-spousal caregivers for patients with end-stage liver disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  9. Review
  10. Observational
  11. Observational
  12. Review
  13. Article
  14. Observational
  15. Review
  16. Article
  17. Article
  18. Observational
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Julie T BidwellOregon Health and Science University School of Nursing, Portland, OR julietbidwell@gmail.com.
Karen S LyonsOregon Health and Science University School of Nursing, Portland, OR.
James O MuddOregon Health and Science University Knight Cardiovascular Institute, Portland, OR.
Kathleen L GradyNorthwestern University Feinberg School of Medicine, Chicago, IL.
Jill M GelowOregon Health and Science University Knight Cardiovascular Institute, Portland, OR.
Shirin O HiattOregon Health and Science University School of Nursing, Portland, OR.
Christopher V ChienUniversity of North Carolina REX Healthcare, Raleigh, NC.
Christopher S LeeOregon Health and Science University School of Nursing, Portland, OR.
Oregon Health & Science University · USNorthwestern University · USRex Hospital · US

Funding

Training in Interventions to Improve Outcomes in Chronic ConditionsT32NR012715 · NINR · EMORY UNIVERSITY · PI GARY, REBECCA A, SONG, MI-KYUNG · 2012 to 2022
$3.2M
Profiling Biobehavioral Responses to Mechanical Support in Advanced Heart FailureR01NR013492 · NINR · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEE, CHRISTOPHER SEAN · 2012 to 2015
$1.4M
Mechanical Circulatory Support in Patient-Caregiver Dyads: A Longitudinal StudyF31NR014760 · NINR · OREGON HEALTH & SCIENCE UNIVERSITY · PI BIDWELL, JULIE THERESA · 2013 to 2016
$110k
NINR NIH HHS F31 NR014760NINR NIH HHS R01 NR013492NINR NIH HHS T32 NR012715
6 · The paper itself

Abstract

backgroundAlthough current guidelines emphasize the importance of social support to the success of left ventricular assist device (LVAD) therapy, few studies examine the influence of the caregiver on patient outcomes or quantify the impact of LVAD caregiving on caregiver outcomes. The purpose of this analysis was to identify patient and caregiver determinants of patient quality of life (QOL) and caregiver strain in response to LVAD therapy. METHODS AND

resultsData on patients receiving LVAD therapy and their caregivers (n=50 dyads) were prospectively collected pre-implantation and 1, 3, and 6 months post-implantation. Growth curve modeling was used to describe change in patient QOL (Kansas City Cardiomyopathy Questionnaire) and caregiver strain (Multidimensional Caregiver Strain Index). Patient QOL improved most in the first month (β=23.22±3.76,

conclusionsA combination of patient and caregiver characteristics predicts patient and caregiver response to LVAD therapy. Including caregiver factors in future studies may be helpful in developing interventions that improve patient and caregiver outcomes, together.

Indexed as

Adaptation, PsychologicalHeart-Assist DevicesQuality of LifeVentricular Function, LeftAdultAgedCaregiversFemaleHeart FailureHumansLongitudinal StudiesMaleMiddle AgedPatientsProspective StudiesRisk Factorscaregiversheart failurequality of lifeventricular assist device

Identifiers

PMID29514804
PMCPMC5907562
OpenAlexW2791839337

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.