Evidence map›Paper›PMID 29514704›Full record

ArticleVeterinary research2018

Decreased STEC shedding by cattle following passive and active vaccination based on recombinant Escherichia coli Shiga toxoids.

Nadine Schmidt, Stefanie A Barth, Jana Frahm, Ulrich Meyer, Sven Dänicke, Lutz Geue, Christian Menge

Open access · goldAbstract read
In one paragraph

Article in Veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. ABToxins · 2022
    Review
  3. The Role ofToxins · 2020
    Review
  4. Article
  5. Review
  6. Molecular Biology ofToxins · 2020
    Review
  7. Treatment Strategies for Infections With Shiga Toxin-ProducingFrontiers in cellular and infection microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nadine SchmidtFriedrich-Loeffler-Institut (FLI)/Federal Research Institute for Animal Health, Institute of Molecular Pathogenesis, Jena, Germany. Nadine.Schmidt@vetmed.uni-giessen.de.ORCID 0000-0003-2923-0574
Stefanie A BarthFriedrich-Loeffler-Institut (FLI)/Federal Research Institute for Animal Health, Institute of Molecular Pathogenesis, Jena, Germany.
Jana FrahmFriedrich-Loeffler-Institut (FLI), Institute of Animal Nutrition, Brunswick, Germany.
Ulrich MeyerFriedrich-Loeffler-Institut (FLI), Institute of Animal Nutrition, Brunswick, Germany.
Sven DänickeFriedrich-Loeffler-Institut (FLI), Institute of Animal Nutrition, Brunswick, Germany.
Lutz GeueFriedrich-Loeffler-Institut (FLI)/Federal Research Institute for Animal Health, Institute of Molecular Pathogenesis, Jena, Germany.
Christian MengeFriedrich-Loeffler-Institut (FLI)/Federal Research Institute for Animal Health, Institute of Molecular Pathogenesis, Jena, Germany.
Friedrich-Loeffler-Institut · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The principal virulence factor of Shiga toxin (Stx)-producing Escherichia coli (STEC), the eponymous Stx, modulates cellular immune responses in cattle, the primary STEC reservoir. We examined whether immunization with genetically inactivated recombinant Shiga toxoids (rStx1

Indexed as

Animal FeedAnimalsBacterial SheddingBacterial VaccinesCattleCattle DiseasesCohort StudiesColostrumDietDietary SupplementsEscherichia coli InfectionsImmunity, Maternally-AcquiredImmunization, PassiveInjections, IntramuscularMaleShiga-Toxigenic Escherichia coliBacterial VaccinesToxoidsVaccines, Synthetic

Identifiers

PMID29514704
PMCPMC5842637
OpenAlexW2790535303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.