Evidence map›Paper›PMID 29514100›Full record

ArticleCell reports2018

Coupling of Rigor Mortis and Intestinal Necrosis during C. elegans Organismal Death.

Evgeniy R Galimov, Rosina E Pryor, Sarah E Poole, Alexandre Benedetto, Zachary Pincus, David Gems

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.3field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 36 citations in OpenAlex.

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  20. Phenotypic Screening inPharmaceuticals (Basel, Switzerland) · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Evgeniy R GalimovInstitute of Healthy Ageing and Department of Genetics, Evolution and Environment, University College London, London, UK.
Rosina E PryorInstitute of Healthy Ageing and Department of Genetics, Evolution and Environment, University College London, London, UK.
Sarah E PooleInstitute of Healthy Ageing and Department of Genetics, Evolution and Environment, University College London, London, UK.
Alexandre BenedettoInstitute of Healthy Ageing and Department of Genetics, Evolution and Environment, University College London, London, UK; Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, Lancaster LA1 4YW, UK.
Zachary PincusDepartment of Genetics and Department of Developmental Biology, Washington University in St. Louis, St. Louis, MO 63110, USA.
David GemsInstitute of Healthy Ageing and Department of Genetics, Evolution and Environment, University College London, London, UK. Electronic address: david.gems@ucl.ac.uk.
University College London · GBWashington University in St. Louis · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Discover determinants of individual longevity and health in C. elegansR00AG042487 · NIA · WASHINGTON UNIVERSITY · PI PINCUS, ZACHARY · 2014 to 2016
$740k
NIA NIH HHS R00 AG042487NIH HHS P40 OD010440Wellcome TrustWellcome Trust 098565/Z/12/Z
6 · The paper itself

Abstract

Organismal death is a process of systemic collapse whose mechanisms are less well understood than those of cell death. We previously reported that death in C. elegans is accompanied by a calcium-propagated wave of intestinal necrosis, marked by a wave of blue autofluorescence (death fluorescence). Here, we describe another feature of organismal death, a wave of body wall muscle contraction, or death contraction (DC). This phenomenon is accompanied by a wave of intramuscular Ca

Indexed as

Adenosine TriphosphateAgingAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCalcium SignalingDeathFluorescenceInsulinInsulin-Like Growth Factor IIntestinesModels, BiologicalMuscle ContractionMusclesMutationNecrosisAdenosine TriphosphateCaenorhabditis elegans ProteinsDAF-2 protein, C elegansInsulinInsulin-Like Growth Factor IReceptor, InsulinagingATPcalciumC. elegansmusclenecrosisorganismal deathpathologyrigor mortis

Identifiers

PMID29514100
PMCPMC5863043
OpenAlexW2791533015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.