ArticlePloS one2018
Pathology and bacteria related to digital dermatitis in dairy cattle in all year round grazing system in Brazil.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Meta-Analysis of Bovine Digital Dermatitis Microbiota Reveals Distinct Microbial Community Structures Associated With Lesions.Frontiers in cellular and infection microbiology · 2021Pooled it
- Bos indicus cattle resistant to digital dermatitis exhibit a balanced proinflammatory cytokine response upon exposure to Treponema phagedenis in contrast to Bos taurus cattle.Veterinary research · 2026Article
- Do Treponemes in Bovine Digital Dermatitis-Associated Claw Horn Lesions Preclude Co-Infection by Pyogenic Bacteria?Microorganisms · 2026Article
- Phenotypic and genomic study of digital dermatitis in UK Holstein heifers.BMC genomics · 2026Article
- Integrated approaches for lameness control in free-stall dairy systems under heat stress and water scarcity.Tropical animal health and production · 2026Review
- Application of 16S rRNA gene amplicon sequencing in the investigation of novel ovine skin lesions in Norway.Frontiers in veterinary science · 2026Article
- Molecular detection and distribution of Treponema species in a commercial dairy cattle herd in Slovakia.Veterinary research communications · 2025Article
- Successful implementation of a risk assessment and mitigation program to control bovine digital dermatitis at the herd-level.Scientific reports · 2025Article
- Metabolic Footprint ofPathogens (Basel, Switzerland) · 2024Article
- Adherence and metal-ion acquisition gene expression increases during infection withInfection and immunity · 2024Article
- Characterization of the Hoof Bacterial Communities of Active Digital Dermatitis Lesions in Feedlot Cattle.Microorganisms · 2024Article
- Bovine Digital Dermatitis: Treponema spp. on trimming equipment and chutes - effect of washing and disinfection.BMC veterinary research · 2024Article
- Molecular Screening for Digital Dermatitis-Associated Treponemes in Bovine Ischaemic Teat Necrosis Lesions and Milk in Dairy Cattle.Pathogens (Basel, Switzerland) · 2024Article
- Local and Systemic Inflammation in Finnish Dairy Cows with Digital Dermatitis.Animals : an open access journal from MDPI · 2024Article
- Effect of zinc source (zinc sulfate or zinc hydroxychloride) on relative abundance of fecalJDS communications · 2022Article
- First Molecular Confirmation ofPathogens (Basel, Switzerland) · 2022Article
- "Non-healing" claw horn lesions in dairy cows: Clinical, histopathological and molecular biological characterization of four cases.Frontiers in veterinary science · 2022Article
- Detection and quantification of bacterial species DNA in bovine digital dermatitis lesions in swabs and fine-needle aspiration versus biopsies.Frontiers in veterinary science · 2022Article
- The Presence ofMicroorganisms · 2021Article
- Identification and Quantification of Bovine Digital Dermatitis-Associated Microbiota across Lesion Stages in Feedlot Beef Cattle.mSystems · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Digital dermatitis (DD) is one of the main causes of lameness in dairy cattle worldwide, and it is frequently reported in high-yielding, free stall dairy herds from regions with a temperate climate. However, DD is also observed with high prevalence in grazing cattle with a low milk yield in tropical regions. To clarify whether these differences have an impact on the etiology of the disease, we studied DD lesions from all year round grazing cattle of mixed breed in Brazil using high-throughput 16S rRNA gene sequencing and fluorescent in situ hybridization. The study included samples from 66 skin lesions and 5 healthy skins collected from five farms. Both techniques showed Treponema spp. to be the most abundant bacteria, present in all but one of the samples with minimal epidermal alterations. We identified eleven different Treponema strains belonging to the six major phylotypes of Treponema which have all previously been identified in DD lesions. Furthermore, we identify Dichelobacter nodosus in DD lesions by gene sequencing and also by fluorescent in situ hybridization in almost half of biopsy specimens in areas with mild epithelial damage and together with Treponema. The present data support the hypothesis that Treponema constitutes the main pathogen responsible for DD, independent of the environment and region where cows are kept, and it further suggests D. nodosus as another potentially important pathogen.
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