Evidence map›Paper›PMID 29513605›Full record

ArticlePsychological science2018

Genetics and Crime: Integrating New Genomic Discoveries Into Psychological Research About Antisocial Behavior.

J Wertz, A Caspi, D W Belsky, A L Beckley, L Arseneault, J C Barnes, D L Corcoran, S Hogan, R M Houts, N Morgan and 6 more

Abstract readTwin Study
In one paragraph

Article in Psychological science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  18. A polygenic score for age-at-first-birth predicts disinhibition.Journal of child psychology and psychiatry, and allied disciplines · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

J Wertz1 Department of Psychology & Neuroscience, Duke University.
A Caspi1 Department of Psychology & Neuroscience, Duke University.
D W Belsky5 Department of Medicine, Duke University School of Medicine.
A L Beckley1 Department of Psychology & Neuroscience, Duke University.
L Arseneault4 Social, Genetic, & Developmental Psychiatry Research Centre, Institute of Psychiatry, Psychology, & Neuroscience, King's College London.
J C Barnes8 School of Criminal Justice, University of Cincinnati.
D L Corcoran3 Center for Genomic and Computational Biology, Duke University.
S Hogan9 Dunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago.
R M Houts1 Department of Psychology & Neuroscience, Duke University.
N Morgan10 Home Office, London, United Kingdom.
C L Odgers11 Sanford School of Public Policy, Duke University.
J A Prinz3 Center for Genomic and Computational Biology, Duke University.
K Sugden1 Department of Psychology & Neuroscience, Duke University.
B S Williams1 Department of Psychology & Neuroscience, Duke University.
R Poulton9 Dunedin Multidisciplinary Health and Development Research Unit, Department of Psychology, University of Otago.
T E Moffitt1 Department of Psychology & Neuroscience, Duke University.

Funding

STALLARD Admin Supp: Predicting Future Care Needs and Costs for Individual Medicare Enrollees with Incident Suspected Alzheimer's DiseaseP30AG034424 · NIA · DUKE UNIVERSITY · PI SCOTT M. LYNCH · 2009 to 2026
$12.2M
Quantifying Individual Differences in Midlife Structural Brain Integrity Associated with Later AD/ADRD RiskR01AG049789 · NIA · DUKE UNIVERSITY · PI AHMAD R. HARIRI, TERRIE E MOFFITT · 2015 to 2026
$10.6M
Is mental disorder a preventable cause of age-related disease? The Dunedin Study.R01AG032282 · NIA · DUKE UNIVERSITY · PI CASPI, AVSHALOM, MOFFITT, TERRIE E · 2009 to 2025
$9.5M
Science CoreP2CHD065563 · NICHD · DUKE UNIVERSITY · PI Giovanna M Merli · 2015 to 2026
$5.7M
Neuropsychological and genomic signatures of violence exposure in childhoodR01HD077482 · NICHD · DUKE UNIVERSITY · PI CASPI, AVSHALOM · 2013 to 2018
$2.8M
Data commons for 'omic, microscopy and analysis core facilitiesS10OD018164 · OD · DUKE UNIVERSITY · PI WRAY, GREGORY A. · 2014 to 2014
$598k
Generating new knowledge to support reversibility interventionsR01AG048895 · NIA · DUKE UNIVERSITY · PI MOFFITT, TERRIE E · 2014 to 2015
$311k
Medical Research Council G1002190Medical Research Council MR/P005918/1NIA NIH HHS R01 AG032282NIA NIH HHS R01 AG048895NIA NIH HHS R01 AG049789NICHD NIH HHS P2C HD065563NICHD NIH HHS R01 HD077482NIH HHS S10 OD018164
6 · The paper itself

Abstract

Drawing on psychological and sociological theories of crime causation, we tested the hypothesis that genetic risk for low educational attainment (assessed via a genome-wide polygenic score) is associated with criminal offending. We further tested hypotheses of how polygenic risk relates to the development of antisocial behavior from childhood through adulthood. Across the Dunedin and Environmental Risk (E-Risk) birth cohorts of individuals growing up 20 years and 20,000 kilometers apart, education polygenic scores predicted risk of a criminal record with modest effects. Polygenic risk manifested during primary schooling in lower cognitive abilities, lower self-control, academic difficulties, and truancy, and it was associated with a life-course-persistent pattern of antisocial behavior that onsets in childhood and persists into adulthood. Crime is central in the nature-nurture debate, and findings reported here demonstrate how molecular-genetic discoveries can be incorporated into established theories of antisocial behavior. They also suggest that improving school experiences might prevent genetic influences on crime from unfolding.

Indexed as

Academic SuccessCriminalsGenome-Wide Association StudyProblem BehaviorAdolescentAdultAntisocial Personality DisorderChildChild, PreschoolConduct DisorderFemaleHumansLongitudinal StudiesMaleMultifactorial InheritanceNew Zealandantisocial behaviorcrimegeneticslongitudinal

Identifiers

PMID29513605
PMCPMC5945301

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.