ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2018
Sex differences in mitochondrial respiratory function in human skeletal muscle.
Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
67 citing papers in PubMed, 1 synthesis or guideline pooled it, 105 citations in OpenAlex.
- Human studies of mitochondrial biology demonstrate an overall lack of binary sex differences: A multivariate meta-analysis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022Pooled it
- Skeletal muscle hypertrophy and enhanced mitochondrial bioenergetics following electrical stimulation exercises in spinal cord injury: a randomized clinical trial.European journal of applied physiology · 2025Trial
- Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults.Physiological reports · 2020Trial
- No effect of beetroot juice supplementation on exercise economy and performance in recreationally active females despite increased torque production.Physiological reports · 2019Trial
- Age and sex shape plasma lipid associations to skeletal muscle mitochondrial respiration and HGeroScience · 2026Article
- Skeletal Muscle Fibre Type Determines Mitochondrial and Metabolic Responses to Hypoxia and Pulmonary Inflammation in Young Adult Rats.Journal of cachexia, sarcopenia and muscle · 2026Article
- Sex- and fiber type-specific remodeling of the muscle proteome implicates CSRP3 in resistance training-induced hypertrophy.Nature communications · 2026Article
- The hallmarks of skeletal muscle health.Nature metabolism · 2026Review
- Morning endurance training induces superior performance adaptations compared with afternoon training in mice.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- Association of mitochondrial oxidative capacity with physical fitness in ageing: the Baltimore longitudinal study of ageing.Age and ageing · 2026Article
- Understanding cardiovascular aging as a disorder of mitochondrial network.The journal of cardiovascular aging · 2026Article
- Body composition components associated with sex differences in resting metabolic rate among Japanese athletes.Frontiers in sports and active living · 2026Article
- Microvascular arteriolar reactivity in response to skeletal muscle contractions in female and male hamsters.Physiological reports · 2025Article
- Sex dimorphism and substrate dependency of liver mitochondrial bioenergetics and HAmerican journal of physiology. Gastrointestinal and liver physiology · 2025Article
- Evolutionary sex bias in cognitive response to new environmental risk factor - PM2.5.Biology of sex differences · 2025Review
- Mitochondria, Sex, and Cardiovascular Disease: A Complex Interplay.International journal of molecular sciences · 2025Review
- Biological sex does not impact intrinsic mitochondrial respiration supported by complexes I and II in human skeletal muscle.Experimental physiology · 2025Article
- Sex- and endurance training-mediated cardiovascular protection through lipids during exercise.Trends in endocrinology and metabolism: TEM · 2025Review
- Menstrual cycle influence on skeletal muscle mitochondrial respiration in humans.Physiological reports · 2025Article
- Mitochondrial and cardiovascular responses to aerobic exercise training in supine and upright positions in healthy young adults: a randomized parallel arm trial.Translational exercise biomedicine · 2025Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitochondrial bioenergetic contributions to sex differences in human skeletal muscle metabolism remain poorly defined. The primary aim of this study was to determine whether mitochondrial respiratory kinetics differed between healthy young men and women in permeabilized skeletal muscle fibers. While men and women displayed similar ( P > 0.05) maximal respiration rates and abundance of mitochondrial/adenosine diphosphate (ADP) transport proteins, women had lower ( P < 0.05) mitochondrial ADP sensitivity (+30% apparent K
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.