ReviewACS chemical neuroscience2018
Prairie Voles as a Model for Understanding the Genetic and Epigenetic Regulation of Attachment Behaviors.
Review in ACS chemical neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed.
- Effects of Classical Music on Behavioral and Physiological Stress Markers in Socially Isolated Prairie Voles.Annals of the New York Academy of Sciences · 2026Article
- A yeast recombination system recapitulates the length polymorphism of a microsatellite implicated in human social behavior.NAR molecular medicine · 2026Article
- Sex-specific disruption of estrogen receptor alpha (ERα) density in the social brain neural network by Firemaster 550.Journal of the Endocrine Society · 2026Article
- Single-library chromosome-scale diploid assemblies of vole genomes resolve a species-specific duplication implicated in pair bonding.bioRxiv : the preprint server for biology · 2026Article
- Folate prevents the autism-related phenotype caused by developmental pyrethroid exposure in prairie voles.bioRxiv : the preprint server for biology · 2024Article
- Comparative analysis of gonadal hormone receptor expression in the postnatal house mouse, meadow vole, and prairie vole brain.Hormones and behavior · 2024Article
- Hereditary convulsions in an outbred prairie vole line.Epilepsy research · 2023Article
- Prairie vole pair bonding and plasticity of the social brain.Trends in neurosciences · 2023Article
- DNA methylation dynamics during pregnancy.Frontiers in cell and developmental biology · 2023Article
- Can Translational Social Neuroscience Research Offer Insights to Mitigate Structural Racism in the United States?Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Review
- Differences in dopamine and opioid receptor ratios in the nucleus accumbens relate to physical contact and undirected song in pair-bonded zebra finches.Behavioral neuroscience · 2022Article
- Genetic ancestry predicts male-female affiliation in a natural baboon hybrid zone.Animal behaviour · 2021Article
- Medial amygdala ERα expression influences monogamous behaviour of male prairie voles in the field.Proceedings. Biological sciences · 2021Article
- Maturation of Social-Vocal Communication in Prairie Vole (Frontiers in behavioral neuroscience · 2021Article
- Paternal deprivation impairs social behavior putatively via epigenetic modification to lateral septum vasopressin receptor.Science advances · 2020Article
- Comparative role of reward in long-term peer and mate relationships in voles.Hormones and behavior · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Over a lifetime, humans build relationships with family, friends, and partners that are critically important for our mental and physical health. Unlike commonly used laboratory mice and rats, Microtine rodents provide a unique model to study the neurobiology underlying pair bonding and the selective attachments that form between adults. Comparisons between monogamous prairie voles and the closely related but nonmonogamous meadow and montane voles have revealed that brain-region-specific neuropeptide receptor patterning modulates social behavior between and within species. In particular, diversity in vasopressin 1a receptor (V1aR) distribution has been linked to individual and species differences in monogamy-related behaviors such as partner preference, mate guarding, and space use. Given the importance of differential receptor expression for regulating social behavior, a critical question has emerged: What are the genetic and epigenetic mechanisms that underlie brain-region-specific receptor patterns? This review will summarize what is known about how the vasopressin (AVP)-V1aR axis regulates social behaviors via signaling in discrete brain regions. From this work, we propose that brain-region-specific regulatory mechanisms facilitate robust evolvability of V1aR expression to generate diverse sociobehavioral traits. Translationally, we provide a perspective on how these studies have contributed to our understanding of human social behaviors and how brain-region-specific regulatory mechanisms might be harnessed for targeted therapies to treat social deficits in psychiatric disorders such as depression, complicated grief, and autism spectrum disorder.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.