ArticleJournal of feline medicine and surgery2019
Comparison of two intramuscular sedation protocols on sedation, recovery and ease of venipuncture for cats undergoing blood donation.
Article in Journal of feline medicine and surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 18 citations in OpenAlex.
- Randomised clinical trial comparing intramuscular alfaxalone and butorphanol sedation with or without midazolam in hyperthyroid cats.Journal of feline medicine and surgery · 2025Article
- Hematological Parameters from the Feline Blood Donor to the Blood Unit: What Changes Are to Be Expected?Animals : an open access journal from MDPI · 2022Article
- 2021 ISFM Consensus Guidelines on the Collection and Administration of Blood and Blood Products in Cats.Journal of feline medicine and surgery · 2021Article
- Effects of Butorphanol With Alfaxalone or Dexmedetomidine on Feline Splenic Size and Appearance on Ultrasound and Computed Tomography.Frontiers in veterinary science · 2021Article
- Feline procedural sedation and analgesia: When, why and how.Journal of feline medicine and surgery · 2020Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of this study was to compare the quality of sedation and recovery, and ease of venipuncture following sedation for feline blood donation using two intramuscular (IM) sedation protocols: alfaxalone/butorphanol (AB) and dexmedetomidine/butorphanol (DB).
methodsThis was an experimental randomized, blinded, crossover study. Ten client-owned healthy cats were recruited to participate in the study. Cats were sedated with AB (alfaxalone 2 mg/kg and butorphanol 0.2 mg/kg) for one donation and DB (dexmedetomidine 10 μg/kg and butorphanol 0.2 mg/kg) for another. Reaction to injection, quality of sedation and quality of recovery were assessed by a blinded observer. Time to lateral recumbency, number of venipuncture attempts, time required for blood collection and time to return to sternal recumbency were recorded. Cats were monitored for evidence of gastrointestinal distress. Each donation consisted of a maximum of 53 ml whole blood drawn over 3-22 mins. Donors received 100 ml subcutaneous lactated Ringer's solution in recovery. Owners, unaware of sedation protocol, were asked to complete a questionnaire evaluating their cat's behavior following sedation.
resultsIM injections were well tolerated by both treatment groups. There was no significant difference between treatment groups in sedation scores for posture ( P = 0.30) or behavior ( P = 0.06). Cats sedated with DB had significantly higher muscle relaxation scores ( P = 0.03) compared with AB. There was no significant difference between treatment groups in time to lateral recumbency ( P = 0.12), number of venipuncture attempts ( P = 0.91) and time for blood draw ( P = 0.29). There was no difference in quality of recoveries between treatment groups based on simple descriptive scores ( P = 0.18) and owner evaluation 24 h following sedation. One cat vomited following administration of DB. CONCLUSIONS AND RELEVANCE: Alfaxalone is a suitable alternative to dexmedetomidine when combined with butorphanol and used as part of an IM sedation protocol for cats undergoing blood donation.
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