Evidence map›Paper›PMID 29512047›Full record

ArticleTechniques in coloproctology2018

Perioperative hyperglycemia: an unmet need within a surgical site infection bundle.

M Gachabayov, A J Senagore, S K Abbas, S B Yelika, K You, R Bergamaschi

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Techniques in coloproctology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06687811 (The Effects of Preoperative Carbohydrate Loading on Perioperative Blood Glucose Levels and Insulin Resistance in Type 2 Diabetes Mellitus Patients Undergoing Elective Surgery), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06687811 nacompletednot on this mapstarted 2023, after this paper: background citation

The Effects of Preoperative Carbohydrate Loading on Perioperative Blood Glucose Levels and Insulin Resistance in Type 2 Diabetes Mellitus Patients Undergoing Elective Surgery

TypeinterventionalSponsorIndonesia UniversityRan2023 to 2024Enrolled44ConditionsDiabetes Mellitus Type 2Armspreoperative carbohydrate loading, Placebo
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.

  1. Pooled it
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  13. Surgical complications in colorectal cancer patients.Annals of medicine and surgery (2012) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

M GachabayovDivision of Colon and Rectal Surgery, Health Sciences Center T18, Suite 046B, State University of New York, 101 Nicolls Road, Stony Brook, NY, 11794, USA.
A J SenagoreDivision of Colon and Rectal Surgery, Health Sciences Center T18, Suite 046B, State University of New York, 101 Nicolls Road, Stony Brook, NY, 11794, USA.
S K AbbasDivision of Colon and Rectal Surgery, Health Sciences Center T18, Suite 046B, State University of New York, 101 Nicolls Road, Stony Brook, NY, 11794, USA.
S B YelikaDivision of Colon and Rectal Surgery, Health Sciences Center T18, Suite 046B, State University of New York, 101 Nicolls Road, Stony Brook, NY, 11794, USA.
K YouDivision of Colon and Rectal Surgery, Health Sciences Center T18, Suite 046B, State University of New York, 101 Nicolls Road, Stony Brook, NY, 11794, USA.
R BergamaschiDivision of Colon and Rectal Surgery, Health Sciences Center T18, Suite 046B, State University of New York, 101 Nicolls Road, Stony Brook, NY, 11794, USA. rcmbergamaschi@gmail.com.
State University of New York · USStony Brook University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to determine whether perioperative stress hyperglycemia is correlated with surgical site infection (SSI) rates in non-diabetes mellitus (DM) patients undergoing elective colorectal resections within an SSI bundle.

methodsAmerican College of Surgeons National Surgical Quality Improvement Program data of patients treated at a single institution in 2006-2012 were supplemented by institutional review board-approved chart review. A multifactorial SSI bundle was implemented in 2009 without changing the preoperative 8-h nil per os, and in the absence of either a carbohydrate loading strategy or hyperglycemic management protocol. Hyperglycemia was defined as blood glucose level > 140 mg/dL. The primary endpoint was SSI defined by the Centers for Disease Control National Nosocomial Infections Surveillance.

resultsOf 690 patients included, 112 (16.2%) had pre-existing DM. Overall SSI rates were significantly higher in DM patients as compared to non-DM patients (28.7 vs. 22.3%, p = 0.042). Postoperative hyperglycemia was more frequently seen in non-DM patients (46 vs. 42.9%). The SSI bundle reduced SSI rates (17 vs. 29.3%, p < 0.001), but the rate of hyperglycemia remained unchanged for DM or non-DM patients (pre-bundle 59%; post-bundle 62%, p = 0.527). Organ/space SSI rates were higher in patients with pre- and postoperative hyperglycemia (12.6%) (p = 0.017). Overall SSI rates were higher in DM patients with hyperglycemia as compared to non-DM patients with hyperglycemia (35.6 vs. 20.8%, p = 0.002). At multivariate analysis DM, chronic steroid use, chemotherapy and SSI bundle were predictive factors for SSI.

conclusionsThis study showed that non-DM patients have a postoperative hyperglycemia rate as high as 46% in spite of the SSI bundle. A positive correlation was found between stress hyperglycemia and organ/space SSI rates regardless of the DM status. These data support the need for a strategy to prevent stress hyperglycemia in non-DM patients undergoing colorectal resections.

Indexed as

Patient Care BundlesAgedBlood GlucoseColonDiabetes MellitusDigestive System Surgical ProceduresFemaleHumansHyperglycemiaIncidenceMaleMiddle AgedPerioperative PeriodPrevalenceRectumRetrospective StudiesBlood GlucoseColorectal resectionPerioperative hyperglycemiaSurgical site infection

Identifiers

PMID29512047
OpenAlexW2790950990

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.