SynthesisObesity surgery2018
Does Bariatric Surgery Affect the Incidence of Endometrial Cancer Development? A Systematic Review.
Synthesis in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Fertility-sparing treatment for atypical endometrial hyperplasia and endometrial cancer.The Cochrane database of systematic reviews · 2025Pooled it
- Intentional weight loss, weight cycling, and endometrial cancer risk: a systematic review and meta-analysis.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2019Pooled it
- Obesityand Gynaecological Cancers, with a Focus on Morbid Obesity: Risk Stratification, Early Diagnosis and Management.Diagnostics (Basel, Switzerland) · 2026Review
- Metabolic Amplification in Endometrial Carcinogenesis: Biological Rationale and Translational Limits of Precision Chemoprevention.Biomedicines · 2026Review
- Future Prospects of Metabolic and Bariatric Surgery: A Comprehensive Review.Healthcare (Basel, Switzerland) · 2024Review
- Bariatric surgery and diabetes: Current challenges and perspectives.World journal of diabetes · 2024Review
- Small molecule targeted therapies for endometrial cancer: progress, challenges, and opportunities.RSC medicinal chemistry · 2024Review
- Review
- The Effectiveness of Metabolic Bariatric Surgery in Preventing Gynecologic Cancer - from Pathophysiology to Clinical Outcomes.Journal of Cancer · 2024Review
- Effect of bariatric surgery on endometrial cancer regression as part of fertility sparing treatment.Cancer reports (Hoboken, N.J.) · 2023Article
- Context-dependent environmental associations with endometrial cancer histotype and genotype.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2023Article
- Glucose metabolic reprogramming and its therapeutic potential in obesity-associated endometrial cancer.Journal of translational medicine · 2023Review
- Fertility-Sparing Approaches in Atypical Endometrial Hyperplasia and Endometrial Cancer Patients: Current Evidence and Future Directions.International journal of molecular sciences · 2022Review
- Bariatric surgery in patients with breast and endometrial cancer in California: population-based prevalence and survival.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2022Article
- The role of bariatric and metabolic surgery in the development, diagnosis, and treatment of endometrial cancer.Frontiers in surgery · 2022Review
- Obesity and Cancer: the Profile of a Population who Underwent Bariatric Surgery.Obesity surgery · 2021Article
- Impact of Bariatric Surgery on Endometrial Cancer Tumor Pathology.Obesity surgery · 2021Article
- Fertility-Sparing Treatment for Atypical Endometrial Hyperplasia and Endometrial Cancer: A Cochrane Systematic Review Protocol.Advances in therapy · 2021Article
- Article
- Cancer Risk After Bariatric Surgery in a Cohort Study from the Five Nordic Countries.Obesity surgery · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity has been linked to an increased prevalence in multiple cancers. Studies have suggested a reduction in the overall risk of cancer after bariatric surgery. We reviewed the evidence for bariatric surgery reducing the risk of endometrial cancer. Data was extracted from PubMed, EMBASE, and Medline to perform a systematic review. Thirty-one full text articles were identified from 265 abstracts. Nine observational studies were relevant to endometrial cancer. In the five controlled studies, 462 of 113,032 (0.4%) patients receiving bariatric surgery versus 11,997 of 848,864 (1.4%) controls developed endometrial cancer, odds ratio of 0.317 (95% CI 0.161 to 0.627) using random effects model (P < 0.001). Bariatric surgery seems to reduce the risk of endometrial cancer; however, more research is required.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.