ArticleInternational journal of colorectal disease2018
Long-term mortality and recurrence in patients treated for colonic diverticulitis with abscess formation: a nationwide register-based cohort study.
Article in International journal of colorectal disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- German guideline diverticular disease/diverticulitis: Part II: Conservative, interventional and surgical management.United European gastroenterology journal · 2022Guideline
- Failure of nonoperative management in patients with acute diverticulitis complicated by abscess: a systematic review.International journal of colorectal disease · 2021Pooled it
- Surgical resection does not avoid the risk of diverticulitis recurrence-a systematic review of risk factors.International journal of colorectal disease · 2021Pooled it
- Natural Language Processing Algorithm Accurately Classifies Diverticulitis-Related Complications and Predicts Long-Term Outcomes.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026Article
- Evidence-based clinical practice guidelines for diagnosis and medical management of acute colonic diverticulitis developed by the Korean Association for the Study of Intestinal Diseases (KASID).Intestinal research · 2026Review
- Clinical relevance of the 3-cm threshold in sigmoid diverticulitis with abscess: consensus or quandary?International journal of colorectal disease · 2024Article
- Diverticulitis is a population health problem: Lessons and gaps in strategies to implement and improve contemporary care.World journal of gastrointestinal surgery · 2023Review
- Outcomes of Patients Hospitalized for Acute Diverticulitis With Comorbid Generalized Anxiety Disorder.Cureus · 2023Article
- Long-term outcomes and risk factors for diverticulitis recurrence after a successful laparoscopic peritoneal lavage in Hinchey III peritonitis.International journal of colorectal disease · 2023Article
- Colonic diverticulitis location is a risk factor for recurrence: a multicenter, retrospective cohort study in Asian patients.Scientific reports · 2022Article
- [Indications for surgical treatment of diverticular disease].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Review
- The Indications for and Timing of Surgery for Diverticular Disease.Deutsches Arzteblatt international · 2020Review
- Do All Patients Require Resection After Successful Drainage of Diverticular Abscesses?Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020Article
- Epidemiology, Pathophysiology, and Treatment of Diverticulitis.Gastroenterology · 2019Review
- Multicentre study of non-surgical management of diverticulitis with abscess formation.The British journal of surgery · 2019Article
- The coroner does not know!International journal of colorectal disease · 2018Article
- Retroperitoneal and Mediastinal Emphysema after Sigmoid Colon Resection.Case reports in gastroenterologyArticle
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe study aimed to investigate long-term mortality, recurrence, and death related to recurrence for patients admitted with acute diverticulitis with abscess formation (Hinchey stage Ib-II).
methodsThe cohort was identified by linking administrative registers for all Danish citizens in years 2000-2012. Patients were identified from ICD-10 discharge codes and stratified according to treatment (antibiotics, percutaneous abscess drainage, or surgery).
resultsFrom 6,641,672 persons, 3148 patients were identified with acute diverticulitis with abscess formation. Survival was comparable between treatment groups with a 1-year survival of 81-83% and a 5-year survival of 66-67% (p = 0.66). Glucocorticoid usage prior to admission increased risk of mortality with hazard ratio 1.64 (95%CI 1.39-1.93), 1.77 (1.20-2.63), and 1.92 (1.07-3.44) for the antibiotics, drainage, and operative treatment group, respectively. Drainage treatment increased risk of recurrence with sub-distribution hazard (SDH) of 1.52 (1.19-1.95) and operative treatment decreased risk with a SDH of 0.55 (0.32-0.93), both compared with antibiotic treatment (p = 0.0001). Recurrence occurred in 23.6% (18.5-30.1%) of patients in the drainage group, 15.5% (13.9-17.3%) in the antibiotics group, and 9.1% (5.1-16.1%) in the operative group. Recurrence-related mortality was 2.0% (0.9-4.4%) for the drainage group, 1.1% (0.7-1.8%) for the antibiotics group, and 0.6% (0.1-4.3%) for the operative group (p = 0.24). Most recurrences and recurrence-related mortality occurred within the first year after primary admission.
conclusionsThis study with complete national data revealed a high mortality and recurrence rate after diverticular abscesses. Survival was comparable between treatment groups, but patients treated with drainage had significantly higher risk of recurrence.
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