Evidence map›Paper›PMID 29511647›Full record

ArticleJournal of exercise rehabilitation2018

Effects of exercise on sexual function and central mechanism in the streptozotocin-induced diabetic rats.

Jae-Min Lee, Tae-Woon Kim, Hye-Sang Park, Sang-Seo Park, Mal-Soon Shin, Yun-Hee Sung, Tae-Beom Seo, Young-Pyo Kim

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of exercise rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jae-Min LeeDepartment of Physiology, College of Medicine, Kyung Hee University, Seoul, Korea.
Tae-Woon KimDepartment of Physiology, College of Medicine, Kyung Hee University, Seoul, Korea.
Hye-Sang ParkDepartment of Physiology, College of Medicine, Kyung Hee University, Seoul, Korea.
Sang-Seo ParkDepartment of Physiology, College of Medicine, Kyung Hee University, Seoul, Korea.
Mal-Soon ShinSchool of Global Sport Studies, Korea University, Sejong, Korea.
Yun-Hee SungDepartment of Physical Therapy, Kyungnam University, Changwon, Korea.
Tae-Beom SeoDepartment of Kinesiology, College of Natural Science, Jeju National University, Jeju, Korea.
Young-Pyo KimDepartment of Kinesiology, College of Natural Science, Jeju National University, Jeju, Korea.
Kyung Hee University · KRJeju National University · KRKyungnam University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes mellitus is associated with the impairment of sexual function including desire and orgasmic dysfunction. Sexual dysfunction in the diabetes mellitus is due to a selective defect of the nitric oxide synthase (NOS) within paraventricular nucleus (PVN). c-Fos is an immediate early gene and c-Fos expression represents neuronal activity in response to various stimuli. In the present study, we investigated the effects of treadmill exercise on sexual behaviors and the expressions of NOS and c-Fos in the PVN were evaluated using streptozotocin (STZ)-induced diabetic rats. Diabetes mellitus was induced by intraperitoneal injection of STZ. The rats in the treadmill exercise groups were made to run on a treadmill for 30 min once a day during 4 weeks. Male sexual behaviors were evaluated by recording the number of mounting, intromission, and ejaculation frequency. The present results revealed that treadmill exercise ameliorated sexual dysfunction in the STZ-induced diabetic rats. Treadmill exercise restored the contents of NOS and c-Fos in the PVN. The improving effect of treadmill exercise on sexual function can be considered as the neuronal activating effect of exercise through increasing expressions of NO and c-Fos.

Indexed as

c-FosDiabetes mellitusNitric oxideParaventricular nucleusSexual dysfunctionTreadmill exercise

Identifiers

PMID29511647
PMCPMC5833952
OpenAlexW2788532110

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.