Evidence map›Paper›PMID 29511556›Full record

ArticleUnited European gastroenterology journal2018

Preoperative prediction of curative surgery of perihilar cholangiocarcinoma by combination of endoscopic ultrasound and computed tomography.

Sara Kammerer, Tobias Meister, Heiner Wolters, Matthias Lessing, Anna Hüsing, Dirk Domagk, Martin Floer, Christian Wilms, Hartmut Schmidt, Norbert Senninger and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in United European gastroenterology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Sara KammererDepartment of Radiology, University of Münster, Muenster, Germany.
Tobias MeisterDepartment of Gastroenterology, HELIOS Albert-Schweitzer Hospital, Göttingen University Teaching Hospital, Northeim, Germany.
Heiner WoltersDepartment of General and Visceral Surgery, University of Münster, Münster, Germany.
Matthias LessingDepartment of Medicine B, University of Münster, Münster, Germany.
Anna HüsingDepartment of Transplant Medicine, University of Münster, Münster, Germany.
Dirk DomagkDepartment of Medicine B, University of Münster, Münster, Germany.
Martin FloerDepartment of Gastroenterology, HELIOS Albert-Schweitzer Hospital, Göttingen University Teaching Hospital, Northeim, Germany.
Christian WilmsDepartment of Transplant Medicine, University of Münster, Münster, Germany.
Hartmut SchmidtDepartment of Transplant Medicine, University of Münster, Münster, Germany.
Norbert SenningerDepartment of General and Visceral Surgery, University of Münster, Münster, Germany.
Gabriele KöhlerDepartment of Pathology, University of Münster, Münster, Germany.
Hauke Sebastian HeinzowDepartment of Transplant Medicine, University of Münster, Münster, Germany.
University of Münster · DEGoethe University Frankfurt · DEHELIOS Albert-Schweitzer-Klinik Northeim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPerihilar cholangiocarcinomas are often considered incurable. Late diagnosis is common. Advanced disease therefore frequently causes questioning of curative surgical outcome.

aimThis study aimed to develop a prediction model of curative surgery in patients suffering from perihilar cholangiocarcinomas based on preoperative endosonography and computer tomography.

methodsA cohort of 81 patients (median age 67 (54-75) years, 62% male) with perihilar cholangiocarcinoma was retrospectively analyzed. Multivariate logistic regression analysis of staging variables taken from the European Staging System was performed and applied to ROC analysis.

resultsThe correlation of predicted rates of eligibility for surgery with actual rates reached AUC values between 0.652 and 0.758 for endosonography and computer tomography (

conclusionsOur predictive web-based model pSurg with inclusion of T, N, M, B, PV, HA and V stage of the recently published European Staging System for perihilar cholangiocarcinoma results in highly significant predictability for curative surgery when combining preoperative endosonography and computer tomography, thus allowing for better patient selection in terms of possibility of curative surgery.

Indexed as

CCCcholangiocarcinomaoperabilitypredictionscore

Identifiers

PMID29511556
PMCPMC5833220
OpenAlexW2618191057

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.