ReviewF1000Research2018
Antibiotic treatment of acute gastroenteritis in children.
Review in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 124 citations in OpenAlex.
- Antimicrobial resistance in community-acquired enteric pathogens among children aged ≤ 10-years in low-and middle-income countries: a systematic review and meta-analysis.Frontiers in microbiology · 2025Pooled it
- Population-level mathematical modeling of antimicrobial resistance: a systematic review.BMC medicine · 2019Pooled it
- Clinical characteristics and outcomes of bacterial and viral gastrointestinal infection by pathogen: a large-scale observational study in United States.Journal of gastroenterology · 2026Article
- Antidiarrheal activity of the 80% methanol extract and solvent fractions of the leaves of Thymus schimperi (Lamiaceae) in mice.Scientific reports · 2026Article
- Evaluating Early Macrolide Therapy in Pediatric Campylobacter Enterocolitis: A Comparative Study.Antibiotics (Basel, Switzerland) · 2026Article
- Gelatin tannate in pediatric infectious gastroenteritis.Translational gastroenterology and hepatology · 2026Review
- Incidence and antimicrobial resistance of non-typhoidal Salmonella enterica in stool samples from children under five in peri-urban Ouagadougou, Burkina Faso.BMC microbiology · 2025Article
- Associations Between BioFire FilmArray Gastrointestinal Panel Results and Clinical Outcomes in Infectious Gastroenteritis.Diagnostics (Basel, Switzerland) · 2025Article
- Surveillance of Common Circulating Enteric Bacteria and Antimicrobial Susceptibility Patterns in Five Satellite Laboratories in Rwanda, 2014-2022.The American journal of tropical medicine and hygiene · 2025Article
- A Game Changer for Acute Gastroenteritis in the Pediatric Emergency Department: Multiplex Stool PCR Test.Journal of clinical laboratory analysis · 2025Article
- Identification and Antibiotic Resistance of Isolates from Poultry Meat and Poultry Meat By-Products Exhibiting CharacteristicAntibiotics (Basel, Switzerland) · 2025Article
- Inappropriate use of antibiotics in the management of diarrhoea in children under five years admitted with acute diarrhoea in four provinces of Mozambique 2014-2019.BMC infectious diseases · 2025Article
- Diagnosing gastrointestinal infections based on cycle threshold cut-offs of PCR.Microbiology spectrum · 2025Article
- Role of phage therapy in acute gastroenteritis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025Review
- Diarrhoeagenic Escherichia coli associated with childhood diarrhoea in Osun state, Nigeria.BMC infectious diseases · 2024Article
- Mothers' Knowledge, Attitudes, and Practices Regarding the Prevention and Management of Diarrhea among Children in Pakistan: A Cross-Sectional Study.The American journal of tropical medicine and hygiene · 2024Article
- Prescribing Antibiotics for Children with Acute Conditions in Public Primary Care Clinics in Singapore: A Retrospective Cohort Database Study.Antibiotics (Basel, Switzerland) · 2024Article
- Tackling salmonellosis: A comprehensive exploration of risks factors, impacts, and solutions.Open veterinary journal · 2024Review
- Study of plasmid mediated quinolone resistance genes among Escherichia coli and Klebsiella pneumoniae isolated from pediatric patients with sepsis.Scientific reports · 2024Article
- Enteric bacterial agents associated with diarrhea and their antimicrobial sensitivity profiles in children under 5 years from mukuru informal settlement, Nairobi, Kenya.BMC infectious diseases · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antibiotic therapy is not necessary for acute diarrhea in children, as rehydration is the key treatment and symptoms resolve generally without specific therapy. Searching for the etiology of gastroenteritis is not usually needed; however, it may be necessary if antimicrobial treatment is considered. The latter is left to the physician evaluation in the absence of clear indications. Antimicrobial treatment should be considered in severely sick children, in those who have chronic conditions or specific risk factors or in specific settings. Traveler's diarrhea, prolonged diarrhea, and antibiotic-associated diarrhea may also require antibiotic therapy. Depending on the severity of symptoms or based on risk of spreading, empiric therapy may be started while awaiting the results of microbiological investigations. The choice of antibiotic depends on suspected agents, host conditions, and local epidemiology. In most cases, empiric therapy should be started while awaiting such results. Empiric therapy may be started with oral co-trimoxazole or metronidazole, but in severe cases parenteral treatment with ceftriaxone or ciprofloxacin might be considered.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.