Evidence map›Paper›PMID 29511526›Full record

ArticleJournal of surgical case reports2018

False-positive radioiodine accumulation in a huge pelvic mass after thyroidectomy for papillary carcinoma, a case report from Syria.

Fatema Alzahraa Almohamad, Tareq Ahmad, Basel Ahmad, Khalid Hussain, Lama Hadid, Majdi Zein, Mohamad Ahmad

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of surgical case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Fatema Alzahraa AlmohamadFaculty of Medicine, Surgery Department, Damascus University, Damascus, Syria.
Tareq AhmadFaculty of Medicine, Surgery Department, Damascus University, Damascus, Syria.
Basel AhmadFaculty of Medicine, Surgery Department, Damascus University, Damascus, Syria.ORCID 0000-0003-3378-334X
Khalid HussainHeart of England NHS Foundation Trust, UK.
Lama HadidEndocrinology Department, Al-Assad University Hospital, Damascus, Syria.
Majdi ZeinDepartment of Nuclear Medicine, Al-Assad University Hospital, Damascus, Syria.
Mohamad AhmadFaculty of Medicine, Surgery Department, Damascus University, Liver Surgery and Transplant Team in Al-Assad University Hospital, Damascus, Syria.
Al Assad University Hospital · SYDamascus University · SYHeart of England NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iodine has always been connected to thyroid gland, and the fact that thyroid tissue traps, organificates and stores iodine more than other tissues is well known, hence the use of radioiodine as a diagnostic and therapeutic tool for thyroid disorders. However, false-positive cases do occur. We present a case of a 34-year-old patient who underwent total thyroidectomy for papillary carcinoma. Results of follow up TSH, thyroglobulin and thyroglobulin antibody tests after surgery lead to two rounds of radioactive iodine. After that, a radioiodine whole-body scan showed high uptake in the pelvis above bladder. Computed tomography scan showed a pelvic heterogeneous mass with some calcifications. Surgical removal and subsequent pathology confirmed the absence of metastasis. The final pathological diagnosis was serous cystadenoma, endometriosis cyst and leiomyoma. As the real cause behind false-positive iodine uptake by these tissues has yet to be determined, careful assessment should be considered in any suspicious case.

Identifiers

PMID29511526
PMCPMC5829570
OpenAlexW2793796974

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.