Evidence map›Paper›PMID 29511488›Full record

ArticleIranian journal of basic medical sciences2018

Amelioration of carbon tetrachloride-induced hepatic injury by emulsified

Wei-Chih Chang, Chang-Tsen Hung, Yuh-Shuen Chen, Chih-Chi Hsueh, Chien-Wei Hou, Horng-Liang Lay

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of basic medical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Wei-Chih ChangGraduate Institute of Bioresources, National Pingtung University of Science and Technology, Pingtung, Taiwan.
Chang-Tsen HungDepartment of Health and Leisure Management, Yuanpei University of Medical Technology, Hsinchu, Taiwan.
Yuh-Shuen ChenDepartment of Food Science and Technology, Hungkuang University, Taichung, Taiwan.
Chih-Chi HsuehDepartment of Biotechnology and Pharmaceutical Technology, Yuanpei University of Medical Technology, Hsinchu, Taiwan.
Chien-Wei HouDepartment of Biotechnology and Pharmaceutical Technology, Yuanpei University of Medical Technology, Hsinchu, Taiwan.
Horng-Liang LayDepartment of Plant Industry, National Pingtung University of Science and Technology, Pingtung, Taiwan.
Yuanpei University · TWNational Pingtung University of Science and Technology · TWHungkuang University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMATERIALS AND

methodsFive groups of eight to ten weeks male rats with a count of ten for each group were studied to evaluate the protection of two kinds of AC extract from hepatic injury. Acute liver injury of rats was induced by injecting 40% carbon tetrachloride (CCl

resultsEAE at 50 mg/kg significantly decreased the serum AST, ALT, IL-1, IL-6, NO, and ROS levels. Both extracts reduced the activation of p-ERK in the liver samples, but EAE inhibited COX-2 and caspase-3 protein expression better than WAE. The EAE ameliorated CCl

conclusionThe hepatoprotection of EAE could be attributed to the antioxidant and anti-inflammatory effects of

Indexed as

Anti-inflammatoryAntioxidantAntrodia cinnamomeaCarbon tetrachlorideHepatoprotectionMAPKs

Identifiers

PMID29511488
PMCPMC5817165
OpenAlexW2784830053

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.