ArticleGastroenterology and hepatology from bed to bench2017
Pancreatic adenocarcinoma protein-protein interaction network analysis.
Article in Gastroenterology and hepatology from bed to bench, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 14 citations in OpenAlex.
- Article
- Molecular mechanism detection of stage I to stage II transition of esophageal squamous cell carcinoma: a system biology approach.Gastroenterology and hepatology from bed to bench · 2024Article
- Side effects of omeprazole: a system biology study.Gastroenterology and hepatology from bed to bench · 2021Article
- Common and differential features of liver and pancreatic cancers: molecular mechanism approach.Gastroenterology and hepatology from bed to bench · 2021Article
- Immunological reactions by T cell and regulation of crucial genes in treated celiac disease patients.Gastroenterology and hepatology from bed to bench · 2020Article
- The Highlighted Role of GAPDH and Nitric-Oxide Synthase Regulator Activity in Proton Beam Irradiated Melanoma BLM Cells.Journal of lasers in medical sciences · 2019Article
- Gene and Biochemical Pathway Evaluation of Burns Injury via Protein-Protein Interaction Network Analysis.Galen medical journal · 2019Article
- The Screening of Critical Related Genes in Celiac Disease Based on Intraepithelial Lymphocytes Investigation: A Bioinformatics Analysis.Galen medical journal · 2019Article
- Gene screening of colorectal cancers via network analysis.Gastroenterology and hepatology from bed to bench · 2019Article
- Insulin dysregulation plays a critical role in colon inflammation: a bioinformatics approach.Gastroenterology and hepatology from bed to bench · 2018Article
- Celiac disease microarray analysis based on System Biology Approach.Gastroenterology and hepatology from bed to bench · 2018Article
- Biochemical pathway analysis of gastric atrophy.Gastroenterology and hepatology from bed to bench · 2018Article
- Protein-Protein Interaction Analysis of Common Top Genes in Obsessive-Compulsive Disorder (OCD) and Schizophrenia: Towards New Drug Approach Obsessive-Compulsive disorder (OCD) and Schizophrenia Comorbidity Gene Analysis.Iranian journal of pharmaceutical research : IJPR · 2018Article
- Introducing Genes With Significant Role in Migraine: An Interactomic Approach.Basic and clinical neuroscienceArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimGene assessment of pancreatic adenocarcinoma disease via protein-protein interaction (PPI) Network Analysis.
backgroundDiagnosis, especially early detection of pancreatic adenocarcinoma as a lethal disease implies more investigation. PPI Network Analysis is a suitable tool to discover new aspects of molecular mechanism of diseases.
methodsIn the present study the related genes to pancreatic adenocarcinoma are studied in the interactome unit and the key genes are highlighted. The significant clusters were introduced by Cluster-ONE application of Cytoscape software 3.4.0. The genes are retrieved from STRING date base and analyzed by Cytoscape software. The crucial genes based on analysis of central parameters were determined and enriched by ClueGO v2.3.5 via gene ontology.
resultsThe number of 24 key genes among 794 initial genes were highlighted as crucial nodes in relationship with pancreatic adenocarcinoma. All of the key genes were organized in a cluster including 216 nodes. The main related pathways and cancer diseases were determined.
conclusionIt was concluded that the introduced 24 genes are possible biomarker panel of pancreatic adenocarcinoma.
Indexed as
Identifiers
29511477PMC5838186W2783023350What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.