Evidence map›Paper›PMID 29511423›Full record

ArticleJournal of clinical medicine research2018

Seroepidemiology of Cytomegalovirus Infection in Pregnant Women in the Central Mexican City of Aguascalientes.

Cosme Alvarado-Esquivel, Maria Del Carmen Terrones-Saldivar, Jesus Hernandez-Tinoco, Maria Daniela Enriqueta Munoz-Terrones, Roberto Oswaldo Gallegos-Gonzalez, Luis Francisco Sanchez-Anguiano, Martha Elena Reyes-Robles, Elizabeth Irasema Antuna-Salcido

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Cytomegalovirus Infection in Pregnancy - Our Experiences.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Cosme Alvarado-EsquivelBiomedical Research Laboratory, Faculty of Medicine and Nutrition, Juarez University of Durango State, Avenida Universidad S/N, 34000 Durango, Mexico.
Maria Del Carmen Terrones-SaldivarCentro de Ciencias de la Salud, Universidad Autonoma de Aguascalientes, Mexico.
Jesus Hernandez-TinocoInstitute for Scientific Research "Dr. Roberto Rivera-Damm", Juarez University of Durango State, Avenida Universidad S/N, 34000 Durango, Mexico.
Maria Daniela Enriqueta Munoz-TerronesCentro de Ciencias de la Salud, Universidad Autonoma de Aguascalientes, Mexico.
Roberto Oswaldo Gallegos-GonzalezCentro de Ciencias de la Salud, Universidad Autonoma de Aguascalientes, Mexico.
Luis Francisco Sanchez-AnguianoInstitute for Scientific Research "Dr. Roberto Rivera-Damm", Juarez University of Durango State, Avenida Universidad S/N, 34000 Durango, Mexico.
Martha Elena Reyes-RoblesCentro de Ciencias de la Salud, Universidad Autonoma de Aguascalientes, Mexico.
Elizabeth Irasema Antuna-SalcidoInstitute for Scientific Research "Dr. Roberto Rivera-Damm", Juarez University of Durango State, Avenida Universidad S/N, 34000 Durango, Mexico.
Autonomous University of Aguascalientes · MXUniversidad Juárez del Estado de Durango · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfection with cytomegalovirus (CMV) during pregnancy may lead to congenital disease. Very little is known about the seroepidemiology of CMV infection in pregnant women in Mexico. We sought to determine the seroprevalence and correlates of CMV infection in pregnant women in Aguascalientes City, Mexico.

methodsThrough a cross-sectional study design, 289 pregnant women were examined for anti-CMV IgG and IgM antibodies in Aguascalientes City, Mexico. A standardized questionnaire was used to obtain the socio-demographic, clinical and behavioral characteristics of the pregnant women. The association between CMV infection and the characteristics of the pregnant women was assessed by bivariate and multivariate analyses.

resultsAnti-CMV IgG antibodies were detected in 259 (89.6%) of the 289 pregnant women studied. None of the 289 pregnant women were positive for anti-CMV IgM antibodies. Seroprevalence of CMV infection was significantly lower (P = 0.03) in pregnant women with reflex impairment (5/8: 62.5%) than in those without this clinical feature (246/272: 90.4%). Seroprevalence of CMV infection was significantly higher (P = 0.03) in pregnant women with 2 - 9 pregnancies (140/150: 93.3%) than in those with only one pregnancy (119/139: 86.2%). Logistic regression analysis of socio-demographic and behavioral variables showed that seropositivity to CMV was associated with contact with children (odds ratio (OR) = 3.56; 95% confidence interval (CI): 1.17 - 10.84; P = 0.02), whereas high (> 150 AU/mL) anti-CMV antibody levels were negatively associated with washing hands before eating (OR = 0.17; 95% CI: 0.05 - 0.63; P = 0.007).

conclusionsWe found a high endemicity of CMV infection in pregnant women in Aguascalientes City, Mexico. Factors associated with CMV infection found in this study may be useful for an optimal planning of preventive measures against CMV exposure in pregnant women.

Indexed as

Cross-sectional studyCytomegalovirusEpidemiologyInfectionMexicoPregnant womenSeroprevalence

Identifiers

PMID29511423
PMCPMC5827919
OpenAlexW2787763003

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.