ReviewJournal of clinical medicine research2018
Primary Small Intestinal Angiosarcoma: Epidemiology, Diagnosis and Treatment.
Review in Journal of clinical medicine research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Angiosarcoma-related cerebral metastases: a systematic review of the literature.Neurosurgical review · 2020Pooled it
- Colonic Angiosarcoma 16 Years After Pelvic Radiotherapy for Cervical Cancer: A Case Report.Cureus · 2026Article
- Stenosing Ileal Angiosarcoma Presenting as Subocclusive Syndrome: A Rare Case Report and Literature Review.Diagnostics (Basel, Switzerland) · 2026Article
- Primary Jejunal Angiosarcoma.ACG case reports journal · 2025Article
- Unexpected Discovery of Small Bowel Angiosarcoma Amidst the Management of Severe Polytrauma: A Case Report.Cureus · 2025Article
- Primary epithelioid angiosarcoma of the jejunum presenting with severe anemia and distant metastasis: a case report and literature review.Frontiers in oncology · 2025Article
- Spontaneous splenic rupture as a primary manifestation of angiosarcoma: a case report.Journal of surgical case reports · 2024Article
- Synchronous Double Primary Angiosarcoma Originating from the Stomach and Rectum: A Case Report and a Literature Review.Archives of Iranian medicine · 2024Review
- Primary small intestine angiosarcoma mimicking Crohn's disease.BMJ case reports · 2024Article
- Primary Epithelioid Angiosarcoma of the Jejunal Mesentery Causing Abdominal Bleeding: Case Report and Literature Review.OncoTargets and therapy · 2024Article
- Angiosarcoma in gastroduodenal tract before and after the treatment with pazopanib: a case report (with video).iGIE : innovation, investigation and insights · 2023Article
- Unexpected Cause of Anemia: Primary Small Intestinal Angiosarcoma.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Article
- Small intestinal angiosarcoma on clinical presentation, diagnosis, management and prognosis: A case report and review of the literature.World journal of gastroenterology · 2023Review
- Article
- Successful endoscopic diagnosis of angiosarcoma of the small intestine: A case report.DEN open · 2022Article
- Newcastle disease virus expressing an angiogenic inhibitor exerts an enhanced therapeutic efficacy in colon cancer model.PloS one · 2022Article
- Gastrointestinal bleeding caused by jejunal angiosarcoma: A case report.World journal of clinical cases · 2020Article
- Primary post-radiation angiosarcoma of the small bowel. Report of a case and review of the literature.Pathologica · 2020Review
- Duodenal angiosarcoma can be misdiagnosed as a Dieulafoy's lesion.Gastroenterology and hepatology from bed to bench · 2020Article
- Outlasting a Rare Duodenal Angiosarcoma.Cureus · 2019Article
Corrections and comments
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Authors and funding
17 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Angiosarcoma is an aggressive mesenchymal sarcoma of endothelial cell origin with high mortality. Its occurrence in the small intestine is exceedingly low. In addition to the rarity of small intestine angiosarcoma, the nonspecific early clinical symptoms obscure the suspicion of such tumors and thereby delay the diagnosis. In a hope to improve the knowledge of this rare but fatal neoplasm, we report one case of angiosarcoma of duodenum and jejunum in a 73-year-old man. Furthermore, we summarize and analyze the common clinical features, tumor markers, treatment, and survival of previous reported cases of this malignancy. Small bowel angiosarcoma occurs more often in men than women (1.6:1). The median age at diagnosis is 68.5 years. The overall median survival time is 150 days; the median survival time in female (300 days) is longer than that of male patients (120 days). Von Willebrand factor (vWF), CD31, CD34, vimentin, and Ulex europaeus agglutinin 1 appear to be the most useful markers for the diagnosis. The majority of the patients underwent surgical resection alone or surgery with subsequent chemotherapy. The patients treated with surgery plus chemotherapy survive longer than those underwent surgical resection only (median 420 days, n = 7 vs. 96.5 days, n = 26, respectively; P = 0.0275). Further studies of more cases are needed for a better understanding of this rare entity, as well as the development of effective strategies for prevention, early diagnosis, and treatment.
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