ArticleScientific reports2018
Relationships of H. pylori infection and its related gastroduodenal morbidity with metabolic syndrome: a large cross-sectional study.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- The Association between Helicobacter pylori Infection and Glycated Hemoglobin A in Diabetes: A Meta-Analysis.Journal of diabetes research · 2019Pooled it
- Helicobacter pylori infection and liver function alterations in individuals undergoing gastric cancer screening: a cohort study.Scientific reports · 2026Article
- Relationship between Helicobacter Pylori infection and metabolic syndrome components in adults.Frontiers in endocrinology · 2025Article
- Association between infection with Helicobacter pylori and metabolic syndrome among diabetic patients attending Jimma medical center in Jimma city, Ethiopia: a cross-sectional study.BMC infectious diseases · 2024Article
- Visualizing endoscopy-generated aerosols with laser light scattering (with videos).Gastrointestinal endoscopy · 2022Article
- Peptic Ulcer Disease Associated with Central Obesity.Journal of personalized medicine · 2022Article
- The association ofHeliyon · 2022Article
- Risk factors for gallstone disease onset in Japan: Findings from the Shizuoka Study, a population-based cohort study.PloS one · 2022Article
- Association of Helicobacter pylori infection with the risk of metabolic syndrome and insulin resistance: an updated systematic review and meta-analysis.Diabetology & metabolic syndrome · 2021Article
- Differences in glycated hemoglobin levels and cholesterol levels in individuals with diabetes according to Helicobacter pylori infection.Scientific reports · 2021Article
- H. pylori is related to NAFLD but only in female: A Cross-sectional Study.International journal of medical sciences · 2021Observational
- Article
- Gastroduodenal Bleeding and Perforation in Diabetic Patients with Metabolic Syndrome (The Results of a 15-Year Observation of City Residents with Intensive Urbanization).Iranian journal of public health · 2019Article
- Association ofExperimental and therapeutic medicine · 2019Article
- Normal body mass index (BMI) can rule out metabolic syndrome: An Israeli cohort study.Medicine · 2019Observational
- Helicobacter pylori infection as a risk factor for serum bilirubin change and less favourable lipid profiles: a hospital-based health examination survey.BMC infectious diseases · 2019Article
- Association of Helicobacter pylori infection with gastroesophageal reflux disease.The Journal of international medical research · 2019Article
- Cost-effectiveness of Helicobacter pylori screening followed by eradication treatment for employees in Japan.Epidemiology and infection · 2018Article
- Review
- Association between type 2 diabetes mellitus andJournal of family & community medicineArticle
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The few published studies on the relationship between Helicobacter pylori infection and metabolic homeostasis were relatively small and yielded inconsistent results. We examined the prevalence of metabolic syndrome in relation to H. pylori infection and its symptoms in a large and unselected population. Coded data from the computerised database of a large health maintenance organisation in Israel were accessed for 147,936 individuals 25-95 years of age who performed the urea breath test during 2002-2012. The classification of metabolic syndrome followed a modified definition of the international diabetes federation. Prevalences of H. pylori infection and metabolic syndrome were 52.0% and 11.4% respectively. H. pylori infected patients had increased likelihood of metabolic syndrome: adjusted odds ratio (aOR) 1.15 (95% confidence intervals (CI) 1.10-1.19), as did patients with gastric ulcer: aOR 1.15 (95% CI 1.03-1.28) vs patients without these conditions. Duodenal ulcer was associated with metabolic syndrome only in persons aged 25-34 years: aOR 1.59 (95% CI 1.19-2.13), but not in older persons (P = 0.001 for heterogeneity). In conclusion, the likelihood of metabolic syndrome appeared significantly increased in relation to H. pylori infection and gastric and duodenal ulcers. These findings suggest that H. pylori long-term gastric inflammation might play a role in metabolic homeostasis.
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