Evidence map›Paper›PMID 29511259›Full record

ArticleScientific reports2018

Plant-made Salmonella bacteriocins salmocins for control of Salmonella pathovars.

Tobias Schneider, Simone Hahn-Löbmann, Anett Stephan, Steve Schulz, Anatoli Giritch, Marcel Naumann, Martin Kleinschmidt, Daniel Tusé, Yuri Gleba

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Plant-Based Systems for Producing Therapeutic Proteins: Current Status and Future Prospects.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026
    Review
  3. Review
  4. Article
  5. The Antibacterial Effect and Mechanism of a Bacteriocin Produced byJournal of microbiology and biotechnology · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Genes · 2020
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tobias SchneiderNomad Bioscience GmbH, Biozentrum Halle, Weinbergweg 22, D-06120, Halle (Saale), Germany.
Simone Hahn-LöbmannNomad Bioscience GmbH, Biozentrum Halle, Weinbergweg 22, D-06120, Halle (Saale), Germany.
Anett StephanNomad Bioscience GmbH, Biozentrum Halle, Weinbergweg 22, D-06120, Halle (Saale), Germany.
Steve SchulzNomad Bioscience GmbH, Biozentrum Halle, Weinbergweg 22, D-06120, Halle (Saale), Germany.
Anatoli GiritchNomad Bioscience GmbH, Biozentrum Halle, Weinbergweg 22, D-06120, Halle (Saale), Germany. giritch@nomadbioscience.com.ORCID 0000-0003-4672-0583
Marcel NaumannFraunhofer Institute for Cell Therapy and Immunology, Department of Drug Design and Target Validation, Biozentrum Halle, Weinbergweg 22, D-06120, Halle (Saale), Germany.
Martin KleinschmidtFraunhofer Institute for Cell Therapy and Immunology, Department of Drug Design and Target Validation, Biozentrum Halle, Weinbergweg 22, D-06120, Halle (Saale), Germany.
Daniel TuséDT/Consulting Group, 2695 13th Street, Sacramento, CA, 95818, USA.
Yuri GlebaNomad Bioscience GmbH, Biozentrum Halle, Weinbergweg 22, D-06120, Halle (Saale), Germany.
Nomad Bioscience (Germany) · DEFraunhofer Institute for Cell Therapy and Immunology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salmonella enterica causes an estimated 1 million illnesses in the United States each year, resulting in 19,000 hospitalizations and 380 deaths, and is one of the four major global causes of diarrhoeal diseases. No effective treatments are available to the food industry. Much attention has been given to colicins, natural non-antibiotic proteins of the bacteriocin class, to control the related pathogen Escherichia coli. We searched Salmonella genomic databases for colicin analogues and cloned and expressed in plants five such proteins, which we call salmocins. Among those, SalE1a and SalE1b were found to possess broad antimicrobial activity against all 99 major Salmonella pathovars. Each of the two salmocins also showed remarkably high potency (>10

Indexed as

Bacterial ProteinsBacteriocinsCloning, MolecularComputational BiologyData MiningFood MicrobiologyFood PreservativesGene ExpressionGenome, BacterialMicrobial Sensitivity TestsPlants, Genetically ModifiedRecombinant ProteinsSalmonella entericaUnited StatesBacterial ProteinsBacteriocinsFood PreservativesRecombinant Proteins

Identifiers

PMID29511259
PMCPMC5840360
OpenAlexW2807074093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.